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Clinical Trials/NCT04340466
NCT04340466
Completed
Not Applicable

French Multicentre Observational Study on SARS-Cov-2 Infections (COVID-19) ICU Management: the FRENCH CORONA Study

Centre Hospitalier Universitaire de Nīmes1 site in 1 country1,003 target enrollmentApril 3, 2020

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Pneumonia, Viral
Sponsor
Centre Hospitalier Universitaire de Nīmes
Enrollment
1003
Locations
1
Primary Endpoint
Mortality at day 28
Status
Completed
Last Updated
5 months ago

Overview

Brief Summary

Since December 2019, a new agent, the SARS-Cov-2 coronavirus has been rapidly spreading from China to other countries causing an international outbreak of respiratory illnesses named COVID-19. In France, the first cases have been reported at the end of January with more than 60000 cases reported since then. A significant proportion (20-30%) of hospitalized COVID-19 patients will be admitted to intensive care unit. However, few data are available for this special population in France.

We conduct a large observational cohort of ICU suspected or proven COVID-19 patients that will enable to describe the initial management of COVID 19 patients admitted to ICU and to identify factors correlated to clinical outcome.

Registry
clinicaltrials.gov
Start Date
April 3, 2020
End Date
July 3, 2020
Last Updated
5 months ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Centre Hospitalier Universitaire de Nīmes
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patients admitted to ICU for suspected or proven SARS-Cov-2 infection, defined by positive SARS-Cov-2 PCR or CT scan images
  • Patient \> or= 18 years

Exclusion Criteria

  • Patient study refusal
  • Patient already enrolled in the present study
  • Patient with respiratory illness with negative COVID-19 CT scan images and negative COVID\_19 PCR

Outcomes

Primary Outcomes

Mortality at day 28

Time Frame: day 28

Mortality at day 28

Secondary Outcomes

  • Patients receiving mechanical ventilation(up to day 28)
  • Vital status(day 28)
  • Antiviral therapy(up to day 28)
  • severe complications(up to day 28)
  • Delay in Microbiological diagnosis(day 1)
  • Imaging(day 1)
  • Antibiotic therapy(day 28)
  • Covid-19 treatments(up to day 28)
  • Patients receiving renal replacement therapy(up to day 28)

Study Sites (1)

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