Effect of Moringa Oleifera Leaves on Glycemic Control of Women With Type 2 Diabetes

Not Applicable

Completed

• Conditions: Type 2 Diabetes
• Interventions: Dietary Supplement: Supplementation of Moringa oleifera leaf powder

• Registration Number: NCT06517602
• Lead Sponsor: University of Milan

Brief Summary

The objective of this clinical trial was to understand whether supplementation of Moringa oleifera leaf powder improved glycemic management in Sahrawi women with type 2 diabetes living in refugee camps. The main question sought to be answered was:

- Does daily supplementation of Moringa oleifera leaf powder, in addition to oral hypoglycemic therapy, improve glycosylated hemoglobin and fasting blood glucose?

Researchers compared Moringa supplementation with no Moringa consumption to see if Moringa oleifera worked to improve glycemic control.

Participants had to:

* Take Moringa oleifera leaves daily or abstain from consuming Moringa for 3 months.

* Consistently take prescribed oral hypoglycemic agents

* Undergo clinical examinations and measurement of biochemical, metabolic and body composition parameters at the time of recruitment and at the end of the study.

Detailed Description

Not available

Study Timeline

• Study Start: 2019-11-07
• Primary Completion: 2020-02-23
• Study Completion: 2020-02-23
• Status Verified: 2024-07
• Study First Submitted: 2024-07-11
• Study First Submitted QC: 2024-07-22
• Last Update Submitted: 2024-07-22
• Study First Posted: 2024-07-24
• Last Update Posted: 2024-07-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 52

Inclusion Criteria

• Diagnosis of type 2 diabetes for at least 1 year
• Absence of advanced retinopathy, terminal renal failure, active diabetic ulcers, amputations, and heart failure
• Treatment with only oral hypoglycemic drugs.

Exclusion Criteria

• Diagnosis of type 1 diabetes
• Pregnancy or lactation
• Treatment with insulin.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Moringa	Supplementation of Moringa oleifera leaf powder	The experimental group received for 3 months a daily supplementation of 10g of Moringa oleifera leaf powder to consume within the two main meals.

Primary Outcome Measures

Name	Time	Method
Fasting glucose	Fasting glucose was measured at recruitment and at the end of the study (three months)
Glycosylated hemoglobin (HbA1c)	Glycosylated hemoglobin was measured at recruitment and at the end of the study (three months)

Secondary Outcome Measures

Name	Time	Method
Hip circumference	Hip circumference were measured at recruitment and at the end of the study (3 months)
BMI	BMI were measured at recruitment and at the end of the study (3 months)
Waist circumference	Waist circumference were measured at recruitment and at the end of the study (3 months)
% body fat	% of body fat were measured at recruitment and at the end of the study (3 months)
Blood pressure	Systolic and diastolic blood pressure were measured at recruitment and at the end of the study (3 months)	Systolic and diastolic blood pressure

Trial Locations

Locations (1)

Dispensaris of Edchedería, Bir Lehlu, Mahbes, and Farsia (Smara camp); 🇩🇿 Tindouf, Algeria