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临床试验/CTRI/2024/01/061675
CTRI/2024/01/061675尚未招募不适用

A comparative study of post-TURP outcomes in patients with BPE-related severe LUTS, Acute urinary retention, and Chronic urinary retention

Kasturba Medical College1 个研究点 分布在 1 个国家目标入组 196 人开始时间: 2024年1月19日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
196
试验地点
1
主要终点
To Study post operative Trial with out catheterization rates, improvement in IPSS-QoL scores, Uroflowmetry parameters among patients with different initial presentations.

研究概览

简要总结

TURP has been the gold standard surgical mode of management for BPE-related

refractory severe LUTS and Urinary retention for many years. The outcomes after TURP

have not been consistent in different sets of patients with different initial presentations. So, this study

aims to obtain a better understanding of the spectrum of presentation of BPO (Severe LUTS, Acute

urinary retention – spontaneous or precipitated Chronic urinary retention – HPCR & LPCR) & post

TURP outcomes in those patients. Many studies have indicated that patients with prolonged duration of

BPE-related LUTS and urinary retention may have poorer post-TURP outcomes. So, in this study, we

shall be looking to answer whether early TURP is to be preferred over prolonged medical management

of BPO before AUR or CUR sets in.

In this study, patients are recruited after obtaining consent and explaining about the study. They are grouped into three groups based on the initial presentation. Baseline data is collected. All patients undergo TURP and post-operative outcome measures are obtained and compared among different groups.

研究设计

研究类型
Observational

入排标准

年龄范围
40.00 Year(s) 至 90.00 Year(s)(—)
性别
Male

入选标准

  • Patients presenting with BPE with Severe LUTS and failed medical management, with Recurrent UTI, with Refractory hematuria, with acute urinary retention, with chronic urinary retention.

排除标准

  • Other causes of bladder outlet obstruction –.
  • urethral stricture,.
  • prostate cancer,.
  • bladder neck contracture.

结局指标

主要结局

To Study post operative Trial with out catheterization rates, improvement in IPSS-QoL scores, Uroflowmetry parameters among patients with different initial presentations.

时间窗: Baseline, Post operative day 2, 1 month post surgery and 3 months post surgery

次要结局

  • Re-catheterization rates(Re Surgery)

研究者

申办方类型
Private medical college
责任方
Principal Investigator
主要研究者

K S Chaitanya krishna

Kasturba Medical College

研究点 (1)

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