Comparing the Effects of Tea Tree Oil (Melaleuca Alternifolia) and Conventional Topical Dressing on Healing of Second-Degree Burn Wounds
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- morphological wound changes
研究概览
简要总结
Tea tree oil (TTO) has been recognized for its effectiveness in treating infected burns, insect bites, and promoting wound healing. This clinical study aimed to compare the impact of Tea tree oil dressings versus conventional ones in the healing process of second degree burns wounds.
详细描述
This quasi-experimental comparative controlled clinical trial was conducted at the Burn Unit of Ras-Elteen General Hospital in Alexandria, Egypt. A purposive sample of 30 adult patients with second-degree burns on the chest, abdomen, upper limbs (excluding hands), and lower limbs (excluding feet) was enrolled from the Emergency and Outpatient Departments. Participants were sequentially assigned to two equal groups:
Control group (n=15): Received conventional dressings (sterile gauze with silver sulfadiazine).
Study group (n=15): Received topical 10% tea tree oil (TTO) ointment applied directly to wounds.Wounds were cleansed with sterile normal saline (0.9%), and non-viable tissue was debrided.
Dressings were changed every other day unless soiled or damp. Burns near joints were maintained in functional positions.Wound assessment was performed on days 7, 14, and 21 post-treatment
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient willing to participate and communicate
- •Newly admitted with recent 2nd-degree burns (superficial or deep) involving ≤10% of TBSA
- •Length of hospital stay of 10 days
排除标准
- •Any associated illnesses that may affect wound healing, such as:
- •Diabetes mellitus (DM)
- •Immune disorders
- •Pre-existing skin conditions (e.g., eczema)
研究组 & 干预措施
conventional dressing
Conventional dressing: Is the routine study hospital's burn dressing technique, utilizing sterile topical gauze dressing that is impregnated with or laid over a topical antibacterial, silver sulphadiazin dressing secured with adhesive tape.
干预措施: tea tree oil ointment (Drug)
结局指标
主要结局
morphological wound changes
时间窗: 3 weeks
assessment of: wound bed, wound margin: color, size, depth, presence of exudates: its amount, color, odor, and type, or scare, edema and granulation tissue formation; in addition to assessment of the wound's surrounding skin condition for: erythema, hotness, tenderness, swelling, separation of deep tissues, fever and peri-wound skin laceration. Each item was rated to score on 2 points Likert scale: 0 = not present and 1= Present. A total score of every patient in both groups was summed up and converted into percent score. to desribe wound healing process as ; complete healing: ; Partial healing: and No healing: where higher percent represent better healing
Local infection scoring system
时间窗: 3 weeks
Local infection scoring system was recorded as: 0= Absence of infection. 1= Presence of local signs of wound infection (redness, hotness, tenderness, purulent discharge and swelling)2 = Presence of systemic wound infection signs (fever, elevated WBCs, ESR and elevated CRP)
次要结局
未报告次要终点