A Comparison Of Home Exercises With Multimodal Real-time Sensory Feedback To The Same Exercise Program With No Enhanced Feedback on Walking Automaticity in People With Parkinson Disease.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 26
- 试验地点
- 2
- 主要终点
- Changes in temporalspatial components of Gait
研究概览
简要总结
People with Parkinson Disease (PWPD) have significant problems with velocity, safety and dual tasking during walking that may be secondary to poor automaticity. Sensory functions, especially visual dependence and proprioceptive integration are critical for efficient walking and are often impaired. This home program compares the use of multimodal sensory feedback during stepping and balance exercises in PWPD to a group without the sensory feedback performing the same basic exercises.
详细描述
Parkinson disease impairs motor and sensory functions. Automaticity of gait is lost increasing the use of higher center control of walking, leading to cognitive fatigue, slower movement and motor errors. People with Parkinson disease (PWPD) improve motor performance when external sensory cues, which bypass the faulty basal ganglia, are used during interventions. Enhancing proprioceptive, visual and vestibular cues that are critical for walking has the potential to improve gait and decrease cognitive fatigue by restoring automaticity.
This is a single-blinded randomized controlled study with repeated measures to evaluate the effects of a home exercise program with or without the addition of multi-modal sensory feedback (MMSF) in real-time on automaticity of gait and balance. PWPDs are randomly assigned to one of 2 home exercise groups. There are two 6 week exercise sessions with a 6 week of no exercises inter-spaced between them. The exercises promote rapid and large movement in stepping activities, balance using self-perturbation through single, leg swings and standing on a compliant surface for sensory re-weighting. People in the experimental group perform the program with real-time with MMSF. Participants are to progress exercises in speed and distance as well as performing with eyes closed to improve proprioceptive processing and automaticity.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
盲法说明
blinded to subject group assignment
入排标准
- 年龄范围
- 21 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Medical diagnosis of Parkinson Disease
- •A score of 26 or higher on the Mini-Mental Status Exam
- •Able to stand from sitting and take 5 steps without assistance
- •People who have been on the same dosages of medication for PD for 3 weeks or longer
排除标准
- •Participating in an exercise program for less than 3 months
- •Plans to change a current exercise program during the study
- •Changes in medications that affect PD or its sequelea
结局指标
主要结局
Changes in temporalspatial components of Gait
时间窗: baseline before exercise training, 6 weeks, 12 weeks and 18 weeks after initiation of exercise
temporal and spacial components of gait measured with Gaitrite Mat
changes in balance
时间窗: baseline before exercise training, 6 weeks, 12 weeks and 18 weeks after initiation of exercise
single leg stance time, time standing on foam eyes closed, Mini-BESTest
Change in cognitive attention needed for gait
时间窗: Baseline, 6 weeks, 12 weeks and 18 weeks after initiation of exercise
3 meter walk test performed at comfortable gait speed once and repeated while subtracting 3s from 100 to assess cognitive attention needed for walking tasks (automaticity)
Change in perceived difficulty during gait and ADLs,
时间窗: Baseline, 6 weeks, 12 weeks and 18 weeks after initiation of exercise
Parkinson Disease Questionnaire (PDQ-39)
次要结局
未报告次要终点
