Home Improvement Initiative of the TRaitement Optimisé Medicamenteux After Hospitalization

Not Applicable

Terminated

• Conditions: Chronic Disease; Surgery; Older Adult; Clinical Pharmacy; Ambulatory Care
• Interventions: Behavioral: EOPC Intervention

• Registration Number: NCT04020692
• Lead Sponsor: University Hospital, Strasbourg, France

Brief Summary

The hypothesis is that the intervention of an operational clinical pharmacy team (EOPC), targeting both patients and hospital and health care professionals, allows: i) to initiate a therapeutic review during hospitalization, ii) to accompany the patients upon hospital discharge, iii) to maintain, in outpatient care, the drug treatments that have been optimized during hospitalization.

The main objective of the study is to demonstrate that the intervention of an EOPC in surgical departments and then in outpatient care makes it possible to maintain, 45 days after the discharge of the patients aged 65 years and over, the chronic outpatient treatments revised and optimized during the hospital stay.

The secondary objectives are to measure the impacts of EOPC's intervention on:

* unexpected readmissions, emergency use, medical complications and adverse drug reactions;

* patient and health professional satisfactions (community pharmacists and physicians);

* the costs of drug treatments in ambulatory care.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2019-07-09
• Study First Submitted QC: 2019-07-15
• Study Start: 2019-07-16
• Study First Posted: 2019-07-16
• Primary Completion: 2023-02-02
• Study Completion: 2023-02-02
• Status Verified: 2024-11
• Last Update Submitted: 2024-11-07
• Last Update Posted: 2024-11-11

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 223

Inclusion Criteria

• Patient (man or woman)
• age ≥ 65 years with more than 3 drugs taken for 3 months, stay in surgery with a duration of ≥ 1 days including urgent surgery;
• affiliated to a social health insurance scheme;
• for whom a return home is possible;
• able to understand the objectives of the research and give informed, dated and signed consent.

Exclusion Criteria

• Patient (man or woman)
• with as a hospital discharge an entry into a nursing home or long-term care called "important medical and technical care (SMTI);
• with cognitive or other problems preventing consent (at the discretion of the geriatric expertise team);
• under the safeguard of justice;
• under tutorship or curatorship.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
"intervention " group	EOPC Intervention	Patient At D0, the patient receives his discharge drugs prescription and benefits from a pharmaceutical counselling. At D+3, he benefits from a telephone follow-up (good understanding of the methods of taking drugs, collection of difficulties). Community pharmacist At D0, he receives the discharge drugs prescription. At D+3, he is contacted to collect information relating to drugs 'dispensation. The attending physician At D0, he is informed of the patient's discharge and his drugs treatment At D45, the data collection is based on telephone interviews \[attending physician, pharmacist and patient (and if applicable the caregiver)\]. It makes possible to collect drugs taken by the patient as well as significant events over the period (acute pathologies, re-hospitalizations, etc.).

Primary Outcome Measures

Name	Time	Method
Compliance of patients' medication intake at 45 days (D45) compared to the discharge prescription (D0): drugs prescribed and taken by patients (chronic disease treatments only)	45 days	Compliance is defined as the absence of discrepancies between D0 and D+45. Conversely, the presence of a discrepancy is defined as the presence of at least one deviation of drug intake at D+45 from D0.

Trial Locations

Locations (2)

Groupe Hospitalier Saint Vincent; 🇫🇷 Strasbourg, France

Les Hôpitaux Universitaires de Strasbourg; 🇫🇷 Strasbourg, France