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Clinical Trials/NCT01739270
NCT01739270
Unknown
Not Applicable

Dexamethasone Added to Levobupivacaine Improves Postoperative Analgesia After Supraclavicular Brachial Plexus Blockade

University Hospital Dubrava1 site in 1 country55 target enrollmentOctober 2012

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Brachial Plexus Anesthesia
Sponsor
University Hospital Dubrava
Enrollment
55
Locations
1
Primary Endpoint
duration of analgesia
Last Updated
10 years ago

Overview

Brief Summary

Adding dexamethasone to local anesthetic will significantly prolong duration of brachial plexus anesthesia and analgesia.

Detailed Description

Operations of upper extremities are often performed in regional anesthesia blocks. Single-injection blocks are effective, but time limited. Adding 4mg of dexamethasone to 0.5% levobupivacaine will significantly prolong duration of brachial plexus anesthesia and analgesia for fracture operations of upper extremity. This effect will result in less opioid use postoperatively.

Registry
clinicaltrials.gov
Start Date
October 2012
End Date
January 2013
Last Updated
10 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
University Hospital Dubrava
Responsible Party
Principal Investigator
Principal Investigator

Jasminka Persec, MD, PhD

Anesthesiology, Resuscitation and Intensive Care Medicine Specialist

University Hospital Dubrava

Eligibility Criteria

Inclusion Criteria

  • patients aged 18 years or older
  • ASA (American Society of Anesthesiologists) physical status I, II or III

Exclusion Criteria

  • refusal of the patients to give informed consent
  • preexisting coagulation disorders
  • local infection at the site of the block
  • neuropathy
  • drug or alcohol abusers
  • known allergy to the drug used in study
  • operation time exceeding six hours

Outcomes

Primary Outcomes

duration of analgesia

Time Frame: 24 hour postoperatively

Duration of analgesia after supraclavicular block

Secondary Outcomes

  • postoperative analgesic consumption(24 hour)

Study Sites (1)

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