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临床试验/NCT06251440
NCT06251440已完成不适用

Transabdominal Fetal Reduction in Higher Order Multiple Pregnancies - a Pioneer Study in Nepal

Grande International Hospital, Nepal1 个研究点 分布在 1 个国家目标入组 108 人开始时间: 2018年2月1日最近更新:
适应症
相关药物

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
108
试验地点
1
主要终点
Transabdominal ultrasonography guided fetal reduction is safe and effective in first trimester

研究概览

简要总结

Multifetal pregnancies are common in in vitro fertilization. Multifetal gestation increases maternal and fetal morbidity and mortality. We perform fetal reduction in our hospital by intra-thoracic injection of potassium chloride. This manuscript is description of our initial experience.

详细描述

Assisted reproductive technology and stimulated conception have led to an increase in the prevalence of high order multifetal pregnancies (MFPs) in recent times. MFPs are associated with high maternal and fetal complications. Fetal mortality and morbidity are due to complications of prematurity. Prevalence of pregnancy induced hypertension, pre-eclampsia, eclampsia, antepartum hemorrhage, post-partum hemorrhage, gestational diabetes and difficult deliveries are more in mother with MFP. Embryo/Fetal reduction in high order MFPs helps in prolongation of gestation. Multifetal pregnancy reduction (MFPR) is secondary prevention of the risks associated with MFP. Trans-abdominal intracardiac injection of KCl is a simple, safe and effective technique for MFPR. We are among the first few centers in Nepal doing MFPR. In this study, we are sharing our initial experience of the procedure.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 45 Years(Adult)
性别
Female
接受健康志愿者

入选标准

  • pregnant females with multifetal gestation who opt to undergo fetal reduction

排除标准

  • who do not give consent

结局指标

主要结局

Transabdominal ultrasonography guided fetal reduction is safe and effective in first trimester

时间窗: 4.5 years

To share initial experience of transabdominal multifetal pregnancy reduction (MFPR) in Nepal

次要结局

未报告次要终点

研究者

发起方
Grande International Hospital, Nepal
申办方类型
Other
责任方
Principal Investigator
主要研究者

PRAJWAL DAHAL

Principal Investigator

Grande International Hospital, Nepal

研究点 (1)

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