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Initial Experience of Transabdominal Fetal Reduction in Nepal

Completed
Conditions
In Vitro Fertilization
Registration Number
NCT06251440
Lead Sponsor
Grande International Hospital, Nepal
Brief Summary

Multifetal pregnancies are common in in vitro fertilization. Multifetal gestation increases maternal and fetal morbidity and mortality. We perform fetal reduction in our hospital by intra-thoracic injection of potassium chloride. This manuscript is description of our initial experience.

Detailed Description

Assisted reproductive technology and stimulated conception have led to an increase in the prevalence of high order multifetal pregnancies (MFPs) in recent times. MFPs are associated with high maternal and fetal complications. Fetal mortality and morbidity are due to complications of prematurity. Prevalence of pregnancy induced hypertension, pre-eclampsia, eclampsia, antepartum hemorrhage, post-partum hemorrhage, gestational diabetes and difficult deliveries are more in mother with MFP. Embryo/Fetal reduction in high order MFPs helps in prolongation of gestation. Multifetal pregnancy reduction (MFPR) is secondary prevention of the risks associated with MFP. Trans-abdominal intracardiac injection of KCl is a simple, safe and effective technique for MFPR. We are among the first few centers in Nepal doing MFPR. In this study, we are sharing our initial experience of the procedure.

Recruitment & Eligibility

Status
COMPLETED
Sex
Female
Target Recruitment
108
Inclusion Criteria
  • pregnant females with multifetal gestation who opt to undergo fetal reduction
Exclusion Criteria
  • who do not give consent

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Transabdominal ultrasonography guided fetal reduction is safe and effective in first trimester4.5 years

To share initial experience of transabdominal multifetal pregnancy reduction (MFPR) in Nepal

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Prajwal Dahal

🇳🇵

Kathmandu, Bagmati, Nepal

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