OCOMOTION: Can we optimise the treatments and services provided across the NHS for long COVID?

Not Applicable

Conditions: COVID-19 (SARS-CoV-2 infection)
Infections and Infestations

Registration Number: ISRCTN15022307

Lead Sponsor: niversity of Leeds

Brief Summary: 2022 Protocol article in https://pubmed.ncbi.nlm.nih.gov/35580970/ (added 18/05/2022) 2023 Protocol article in https://pubmed.ncbi.nlm.nih.gov/37553189/ (added 09/08/2023) 2024 Results article in https://pubmed.ncbi.nlm.nih.gov/38616276/ (added 15/04/2024)

Detailed Description: Not available

Recruitment & Eligibility

Status: Ongoing

Sex: All

Target Recruitment: 5000

Inclusion Criteria

Current participant inclusion criteria:
Task 1.1. There are no demographic restrictions on eligibility, other than all professional members of the QI collaborative must by definition be of working age. Patient members of the QI collaborative will need to be at least 18 years of age.
Task 1.2. The LOCOMOTION study is not evaluating healthcare services for children. All participants recruited to Task 1.2 must be at least 18 years of age.
Task 1.3. All participants must be at least 18 years of age, and be able consent and participate in an interview (in person or virtually). Key Informants must have experience of working within health inequalities and Long Covid.
Task 1.4. All patient and HCP participants must be 18 years or older and willing to participate. For employers to participate, consent must have been granted by the employee. For phase 2 of the study, participants must have experience with delivering (Clinical Research Fellow) or
completing (as a patient) the vocational rehabilitation programme.
Task 1.5. People who are involved in peer-support activity or key stakeholders in LC care.
Task 2.1.
1. Patients will be included who are 18 years and over whom are willing and able to participate in the study, i.e. able to complete the ecological momentary assessment and use the wearable technology.
2. Participants must have capability to provide informed consent and have English language use to the level of conducting health consultations.
3. Participants will not be included or excluded based on past or current illness or medication at the time of the presumed covid infection, however they will be asked to describe these at the start of this study.
Task 2.2. Patients aged 18 and over and who are receiving care for Long Covid symptoms at one of the participating LC sites.
Task 2.3. 18 years or older, no pre-existing chronic condition with autonomic dysfunction, and able to complete the aAP test with their own BP machine.
Task 3.1 Uses routine data and all available data will be used unless a patient has opted out of data sharing.

Previous participant inclusion criteria:
Task 1.1. There are no demographic restrictions on eligibility, other than all professional members of the QI collaborative must by definition be of working age. Patient members of the QI collaborative will need to be at least 18 years of age.
Task 1.2. The LOCOMOTION study is not evaluating healthcare services for children. All participants recruited to Task 1.2 must be at least 18 years of age.
Task 1.3. All participants must be at least 18 years of age, and be able consent and participate in an interview (in person or virtually). Key Informants must have experience of working within health inequalities and Long Covid.
Task 1.4. All patient and HCP participants must be 18 years or older and willing to participate. For employers to participate, consent must have been granted by the employee. For phase 2 of the study, participants must have experience with delivering (Clinical Research Fellow) or completing (as a patient) the vocational rehabilitation programe.
Task 2.1.
1. Patients will be included who are 18 years and over whom are willing and able to participate in the study, i.e. able to complete the ecological momentary assessment and use the wearable technology.
2. Participants must have capability to provide informed consent and have English language use to the level of conducting health consultations.
3. Participants will not be included or exc

Exclusion Criteria

Task 1.1. Potential participants with no experiences of long covid healthcare provision will be excluded and will not be eligible to take part in this phase of the LOCOMOTION study.
Task 1.2
1. Potential participants with no experiences of long covid healthcare provision will be excluded and will not be eligible to take part in this phase of the LOCOMOTION study.
2. Patients without capacity to consent for themselves will not be eligible for this phase of the LOCOMOTION study.
3. Patients under the age of 18 will not be eligible to take part in this phase of the LOCOMOTION study.
Task 1.3. Patients who are unable to consent and those under the age of 18 will not be eligible to participate in qualitative interviews. Patients currently receiving care and rehabilitation from a Long Covid clinic will also be excluded.
Task 1.4. Patients who are unable to consent and under the age of 18. Patients will be excluded from Phase 2 of the study if they have not completed the LOCOMOTION Vocational Rehabilitation program.
Task 2.1. Participants will be excluded who are under 18 years old, unable to attend the rehabilitation Centre, unable to use the ecological momentary assessment App technology or use the wearable technology, are pregnant, have a known previous diagnosis of dementia or cognitive impairment preventing participation in the use of the EMA or wearable technologies, or are unable to understand the language used in the EMA.
Task 2.2. Inability to independently complete electronic or paper-based outcome measures, questionnaires or other research-based paperwork, and those patients who are unable to give Informed Consent.

Study & Design

Study Type: Observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
ong COVID management measured using the C19-YRS (Yorkshire Rehabilitation Scale) at 3-monthly intervals

Secondary Outcome Measures

Name	Time	Method
1. Quality of life measured using EQ5D (Euroqol Quality of Life 5 Dimensions) at 3-monthly intervals<br>2. Qualitative data will also be collected to understand the patient experience of the condition and views on the care received using interviews at 12 months