The Use of Drospirenone/Estetrol in Random Start Rapid Preparation of Endometrium Before Office Hysteroscopic Polypectomies: a Multicenter, Prospective, Randomized Study
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 80
- 试验地点
- 2
- 主要终点
- Quality of endometrial preparation
研究概览
简要总结
The presence of a thin endometrium plays an important role in enabling the best conditions for hysteroscopic surgery. Recently, for this purpose, many studies have evaluated the effect of preoperative administration of a variety of drugs. We explored the efficacy of random started 14-day administration of drospirenone/estetrol, in rapid preparation of endometrium for hysteroscopic polypectomy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Patients with endometrial polyps.
排除标准
- •Patients with other endometrial pathologies.
研究组 & 干预措施
Intervention
Patients with endometrial polyps underwent hysteroscopic polipectomy after starting 14-day treatment with oral drospirenone/estetrol 3mg/14.2mg at any time of the menstrual cycle.
干预措施: drospirenone/estetrol 3mg/14.2mg (Drug)
结局指标
主要结局
Quality of endometrial preparation
时间窗: Intraoperatively
Quality of endometrial preparation assessed visually intraoperatively by the surgeon using a visual analog scale from 0 to 5.
次要结局
未报告次要终点
研究者
Andrea Etrusco
Principal investigator
University of Palermo