CTRI/2025/12/099835尚未招募不适用
The Effect Of Alcohol Containing Mouthwash On Salivary Nitrate Reducing Capacity In Normotensive Individuals
AB Shetty Memorial Institute of Dental Sciences NITTE University1 个研究点 分布在 1 个国家目标入组 36 人开始时间: 2026年2月1日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 36
- 试验地点
- 1
研究概览
简要总结
Research Question: Will alcohol content in a mouthwash have an effect on salivary nitrate reducing capacity?
Objectives:
To determine effect on salivary nitrate reducing capacity due to alcohol-based mouthwash use.
To determine effect on salivary nitrate reducing capacity due to aqueous-based mouthwash use.
To compare the effects of alcohol-based and aqueous based mouthwash.
Significance: Oral commensal bacteria reduce nitrates(from diet/saliva) to nitrites. Nitrites are further reduced to nitric oxide in the gut. Nitric oxide is a powerful vasodilator and contributes to blood pressure reduction.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 30.00 Year(s)（—）
- 性别
- All
入选标准
- •Healthy normotensive individuals Prescribed de-sensitizing mouthwashes for sensitive teeth Fasting serum glucose 70-125g/dl BMI between 18-25 No known systemic co-morbidities Written informed consent freely given.
排除标准
- •Tobacco users Periodontitis patients Hypertensive Diabetic/Pre-diabetic Obesity Pregnancy.
研究者
Eesha
K.S. Hegde Medical Academy
研究点 (1)
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