A single center two part study in healthy adult male subjects to determine the human mass balance and pharmacokinetics of a single oral dose of 14C-KHK75801 (Part 1) and to assess the absolute bioavailability based on the pharmacokinetic parameters of a single intravenous microdose of 14CKHK7580 following a single oral dose of KHK7580 (Part 2)
Completed
- Conditions
- chronic kidney diseasessecondary hyperparathyroidism1003394910038430
- Registration Number
- NL-OMON41144
- Lead Sponsor
- Kyowa Hakko
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 11
Inclusion Criteria
healthy male subjects
18-45 yrs, inclusive
BMI: 18.0-30.0 kg/m2, inclusive
Exclusion Criteria
Suffering from hepatitis B, hepatitis C, cancer or HIV/AIDS. In case of participation in another drug study within 60 days before the start of this study or being a blood donor within 60 days from the start of the study. In case of donating more than 1.5 liters of blood in the 10 months prior the start of this study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method