The Impact of E-liquid Nicotine Content on Reinforcement in Current Smokers
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 主要终点
- Product Evaluation Questionnaire
研究概览
简要总结
Participants will complete a phone screen and then one laboratory session. After completing in-person screening assessments, eligible participants will complete additional questionnaires. Participants will then choose an e-liquid flavor to use for the rest of the session. Participants will then sample two e-liquids that vary in nicotine content from little or no nicotine to a moderate level of nicotine, and questionnaires evaluating the subjective effects of each one. Participants will then complete a preference assessment where they choose between the two e-liquids. Participants will be blind to the nicotine contents.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •At least 18 years old
- •Daily cigarette smoking
- •Have tried vaping devices on a minimum of one lifetime occasion
排除标准
- •Unwilling to use a vaping device during the session
- •Break alcohol level > 0.01 (g/dL)
- •Pregnant, trying to become pregnant, or breastfeeding
- •Systolic BP greater than or equal to 160 mm/Hg or below 90 mm/Hg
- •Diastolic BP greater than or equal to 100 mm/Hg or below 50 mm/Hg
- •Heart rate greater than or equal to 105 bpm or lower than 45 bpm
- •A current upper respiratory infection, recent cardiac event (in the last year), Buerger disease, irregular heartbeat or arrhythmia within the last year, previous allergic or adverse reaction to nicotine
研究组 & 干预措施
E-liquid Group
Participants will sample two different e-liquids.
干预措施: E-liquid sampling and preference assessment (Behavioral)
结局指标
主要结局
Product Evaluation Questionnaire
时间窗: One Day
Ratings of the two e-liquids on a self-report questionnaire
次要结局
- Preference Assessment(One Day)
- Vaping Purchase Task(One Day)
- Perceived Health Risk Questionnaire(One Day)