NL-OMON53305招募中不适用
Assessing Frequency of HLA-Genotype and Tumor Antigen Expression in Subjects with Relapsed/Refractory, Advanced-Stage Solid Tumors that may Qualify for Novel T Cell Receptor Based Therapies - Assessing Frequency of HLA-Genotype for TCR Based Therapies
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- T-knife GmbH
- 入组人数
- 400
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •1. Signed written informed consent.
- •2. Histologically or cytologically confirmed diagnosis of relapsed/refractory,
- •advanced stage solid tumor that may express MAGE-A1.
- •3. Subject received at least one line of approved systemic therapy and is
- •declared to be in a non-curable disease state as per treating physician*s
- •current assessment.
- •4. Availability of a stored, accessible tumor sample for IHC.
- •5. Ability to provide a blood sample.
- •6. Age >= 18 years.
- •7. Life expectancy > 6 months as per treating physician*s assessment.
排除标准
- •1. Any bleeding or coagulation disorder or other condition that would present
- •the subject with an undue risk when undergoing a venous blood draw.
- •2. Any other condition that could interfere with subject's safety, obtaining
- •informed consent, or compliance to the screening study procedures.
- •3. Presence of any organ toxicities or other conditions that would preclude
- •intense future anticancer treatments such as required for T cell receptor
研究者
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