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Clinical Trials/NCT01148186
NCT01148186
Terminated
Phase 4

The Patient as a Driver of Change: an Intervention Study to Reduce the Use and Impact of Potentially Inappropriate Medications Among Older Adults

Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal1 site in 1 country300 target enrollmentJune 2010

Overview

Phase
Phase 4
Intervention
Not specified
Conditions
Polypharmacy
Sponsor
Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal
Enrollment
300
Locations
1
Primary Endpoint
Complete discontinuation of the targeted potentially inappropriate medication (e.g. benzodiazepines, oxybutynin)
Status
Terminated
Last Updated
12 years ago

Overview

Brief Summary

An educational intervention targeting community-dwelling older adults will lead to a reduction in potentially inappropriate prescriptions (e.g. benzodiazepines, oxybutynin).

Cessation of potentially inappropriate medications (e.g. benzodiazepines, oxybutynin)will lead to improved cognitive outcomes in older adults.

Detailed Description

This study tests the effectiveness of a knowledge transfer tool for empowering patients to engage in collaborative discontinuation of potentially inappropriate medication with their pharmacist and/or physician

Registry
clinicaltrials.gov
Start Date
June 2010
End Date
May 2013
Last Updated
12 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal
Responsible Party
Principal Investigator
Principal Investigator

Cara Tannenbaum

Dr.

Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal

Eligibility Criteria

Inclusion Criteria

  • 65 year old human adults
  • who fill a prescription for at least 5 medications
  • community dwelling
  • chronic use (3 months or longer) of at least one potentially inappropriate medication (e.g. benzodiazepine, oxybutynin)

Exclusion Criteria

  • patients with severe mental illness, dementia and epilepsy
  • concomitant consumption of any other antipsychotic medication (including lithium, olanzapine, clozapine, quetiapine, risperidone, haloperidol etc.)
  • concomitant consumption of any antiepileptic (including carbamazepine, valproate, gabapentin, lamotrigine, topiramate, oxcarbazepine etc.)
  • concomitant consumption of a cholinesterase inhibitor or memantine

Outcomes

Primary Outcomes

Complete discontinuation of the targeted potentially inappropriate medication (e.g. benzodiazepines, oxybutynin)

Time Frame: 6 months post-intervention

Secondary Outcomes

  • Cognitive function(6-months post-intervention)
  • Sleep efficiency(6-months)
  • incontinence-related self-efficacy(6-months post-intervention)
  • frequency of urinary incontinence episodes(6-months post-intervention)

Study Sites (1)

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