Role of intestinal Acetate Production in human Appetite and Insulin Sensitivity - APRAISE-study

Academisch Medisch Centrum0 个研究点目标入组 54 人开始时间: 待定最近更新: 2024年4月15日

适应症

试验速览

暂无简介。

•- Part of HELIUS study and has given permission to be approached for new studies
•- Stable body weigh (<5% reported weight change during the previous 3 months)
•- Age 18-65
•- Caucasian
•- Able and willing to give informed consent

•- Use of corticosteroids, antibiotics and other immunomodulating medication in last 3 months
•- current XTC, amphetamine, nicotine or cocaïne abuse
•- Alcohol abuse (>3 units per day)
•- Contraindication for MRI (pregnancy, neurological illness, malignancy, history of major heart disease, history of major renal disease, breastfeeding, paecmaker and metals contraindicated for MRI present in the body).
•- Expected prolonged compromised immunity (due to recent cytotoxic chemotherapy or HIV infection with a CD4 count <240)
•- Presence of inflammatory bowel disease (IBD)
•- Inability to understand the study protocol, give informed consent or participate adequately in study protocol.

发起方