Comparison of topical meloxicam vs topical diclofenac in knee osteoarthritis pain management: a clinical trial
Phase 2
Recruiting
- Conditions
- Knee Osteoarthritis.Osteoarthritis of knee
- Registration Number
- IRCT20190810044500N15
- Lead Sponsor
- Yazd University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Age over 40 years old
Primary osteoarthritis
Pain for more than half of the previous month during one of the following activities: walking, climbing stairs, standing up or sleeping on a bed or mat during the night
Radiographic evidence confirms tibiofemoral or patellofemoral osteoarthritis
Score 40 on a WOMAC scale as a basis.
Exclusion Criteria
No intra-articular injection of hyaluronic acid / glucocorticoid over the last six months
No positive pregnancy test or pregnancy plan during the study
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Joint range of motion. Timepoint: At baseline and 7 and 14 days after starting topical meloxicam and topical diclofenac. Method of measurement: Western ontario and mc master universities osteoarthritis index and Knee Injury and Osteoarthritis Outcome Score.;Pain. Timepoint: At baseline and 7 and 14 days after starting topical meloxicam and topical. Method of measurement: Western ontario and mc master universities osteoarthritis index and Visual Analogue Scale and Knee Injury and Osteoarthritis Outcome Score.;Inflammation. Timepoint: At baseline and 7 and 14 days after starting topical meloxicam and topical. Method of measurement: Western ontario and mc master universities osteoarthritis index and Knee Injury and Osteoarthritis Outcome Score.
- Secondary Outcome Measures
Name Time Method