CTRI/2017/10/010272尚未招募2 期
Docetaxel and Carboplatin (DC) versus 5-Flurouracil, Epirubicin, Cyclophosphamide (FEC) and Docetaxel (D)as neoadjuvant chemotherapy in triple negative, non-metastatic breast cancer: a randomized trial.
Jawaharlal Institute of Post Graduate Medical Education and research0 个研究点目标入组 0 人开始时间: 待定最近更新:
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •1.Newly diagnosed, Histologically confirmed Triple negative Breast cancer ER <1%, PR <1% (IHC), HER2 negativity is defined as IHC 0-1+, or [IHC 2+ and FISH negative].
- •2. Stages 2 and 3 according to AJCC edition7,( see appendix 1. )
- •3. Has provided written Informed Consent for participation in this trial
- •4. Adequate Haematological, renal, hepatic and pulmonary functions as defined by, examples
- •ï?? Absolute neutrophil count (ANC, segs + bands), 1.5 x 109/L
- •ï?? Platelet count, 100 x 109/L
- •ï?? Total bilirubin, 1.5 x upper normal
- •ï?? Alanine aminotransferase (ALT), 2.5 x upper normal limit
- •ï?? Calculated creatinine clearance > 60ml/min (Cockcroft-Gault formula )
- •5. An ECOG performance status score of [0,1]
- •6. Participants capable of childbearing are using adequate contraception
- •7. Available for follow up
排除标准
- •1. Male Breast cancer
- •2. Her2 neu 2+ but not confirmed with FISH
- •3. Women who are pregnant or lactating.
- •4. Past or current history of another malignancy
- •5. Previous radiotherapy
研究者
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