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Clinical Trials/NCT05878002
NCT05878002
Recruiting
Not Applicable

"Cognitive, Motor and Sleep Evaluation in Patients With Ischemic Stroke of Basal Ganglia After Thrombectomy"

Fondazione Policlinico Universitario Agostino Gemelli IRCCS1 site in 1 country300 target enrollmentApril 12, 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Post-stroke Disorders
Sponsor
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Enrollment
300
Locations
1
Primary Endpoint
Post-stroke cognitive dysfunction
Status
Recruiting
Last Updated
2 years ago

Overview

Brief Summary

The goal of this interventional study is to learn about the clinical outcomes of acute ischemic stroke treated with mechanical thrombectomy resulting in a selective ischemia of the basal ganglia. The main question it aims to answer is:

• defining the prevalence and clinical features of possible cognitive, motor and sleep disfuncions occuring after acute ischemic stroke treated with thrombectomy

Participants will be tested for cognitive, movement and sleep disorders in the acute phase and successively in the long term follow-up.

Registry
clinicaltrials.gov
Start Date
April 12, 2023
End Date
April 2034
Last Updated
2 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • participant's age ≥ 18 years
  • acute ischemic stroke due to occlusion of proximal middle cerebral artery successfully treated with mechanical thrombectomy (mTICI ≥ 2B)
  • signature of specific written informed consent

Exclusion Criteria

  • unstable clinical conditions
  • personal history of cognitive decline before the acute ischemic stroke

Outcomes

Primary Outcomes

Post-stroke cognitive dysfunction

Time Frame: Within 72 hours

Assessment through the MoCA (Montreal Cognitive Assessment) score of cognitive dysfunction in patients with acute ischemic stroke treated with mechanical thrombectomy

Study Sites (1)

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