Risk Factors of POCD in General Anesthesia Patients Underwent Noncardiac and Non Neurological Procedures.

Completed

• Conditions: Undergoing General Anaesthesia
• Interventions: Other: Questionaire

• Registration Number: NCT04215263
• Lead Sponsor: Indonesia University

Brief Summary

The study was a prospective cohort study to assess the effect of age, duration of anesthesia, repeated surgery, and type of surgery on cognitive impairment in 108 geriatric patients (≥60 years) who underwent general anesthesia for non-neurologic noncardiac surgery.

Detailed Description

The study was a prospective cohort study, assessing the effect of age, duration of anesthesia, repeated surgery, and type of surgery on cognitive impairment in 108 geriatric patients (≥60 years) who underwent general anesthesia for non-neurologic noncardiac surgery. The study used cognitive tests such as RAVLT, TMT, and Digit span tests. POCD definition is reduction in postoperative cognitive function by as much as 20% at a minimum of 2 cognitive tests.

Study Timeline

• Study Start: 2019-05-01
• Primary Completion: 2019-07-05
• Study Completion: 2019-07-05
• Study First Submitted: 2019-12-30
• Study First Submitted QC: 2019-12-30
• Study First Posted: 2020-01-02
• Status Verified: 2020-02
• Last Update Submitted: 2020-02-19
• Last Update Posted: 2020-02-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 109

Inclusion Criteria

• geriatric patient (age over 60) underwent noncardiac non-neurological procedure under general anesthesia
• patient can do reading and writing
• patient can speak in Bahasa
• signing informed consent

Exclusion Criteria

• patient with cognitive impairment or psychiatric disorder such as delirium, amnesia, anxiety disorder, or depression.
• patient under psychotropic drugs or narcotics.
• patient with history of brain tumor, head injury or motoric disturbance and disability that can disturbed neurocognitive test

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Geriatric patient underwent general anesthesia procedure	Questionaire	geriatric patients (≥60 years) ware assessed for cognitive impairment after general anesthesia for non-neurologic noncardiac surgery.

Primary Outcome Measures

Name	Time	Method
Mini International Neuropsychiatric Interview	7 days	Score was assessed using 6 forms

Trial Locations

Locations (1)

Indonesia University; 🇮🇩 Jakarta, DKI Jakarta, Indonesia