The Effect of Regional Anesthesia Techniques on Brain Tissue Oxygenation in Thoracic Surgery

Not Applicable

Completed

• Conditions: Thoracic Surgery; Epidural Anesthesia; Cerebral Oxygen Saturation
• Interventions: Device: Regional oximetry probe; Procedure: Thoracic Epidural block

• Registration Number: NCT04373174
• Lead Sponsor: Bursa Yüksek İhtisas Education and Research Hospital

Brief Summary

Today, it is preferred that the lung with pathology for thorax surgery is not under ventilation during operation in terms of reliability and ease of operation.

For this reason, the anesthesia approach is characteristic and it is ensured that the single lung is not ventilated during the operation by means of specially manufactured intubation tubes. This application can disrupt tissue oxygenation due to both Operation position and single lung ventilation.

Thoracic epidural analgesia, which is applied as the gold standard of Thoracic Surgery, is applied prior to the operation and is provided to assist in postoperative analgesia.

Detailed Description

The aim of this study was to investigate the effect of thoracic epidural analgesia method on brain tissue oxygenation in patients with single lung ventilation.

Study Timeline

• Study First Submitted: 2020-04-30
• Study First Submitted QC: 2020-04-30
• Study Start: 2020-05-01
• Study First Posted: 2020-05-04
• Primary Completion: 2021-04-01
• Study Completion: 2021-05-15
• Status Verified: 2023-01
• Last Update Submitted: 2023-01-07
• Last Update Posted: 2023-01-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Patients who were in the American Society of Anesthesiologists (ASA) I-III class
• Underwent Thoracic Surgery

Exclusion Criteria

• Local anesthetic allergy,
• Bleeding is a diathesis disorder
• Allergic to the drugs used,
• Patients who are not reluctant to participate in the study,
• Presence of infection in the block area,
• Patients whose body mass index is over 30

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Group E	Regional oximetry probe	Thoracic Epidural block + Regional oximetry probe will be placed in the frontal area of the head
Group E	Thoracic Epidural block	Thoracic Epidural block + Regional oximetry probe will be placed in the frontal area of the head
Group P	Regional oximetry probe	Regional oximetry probe will be placed in the frontal area of the head

Primary Outcome Measures

Name	Time	Method
rso2	peroperative 2 hours	Regional oximetry probe will be placed in the frontal area of the head

Secondary Outcome Measures

Name	Time	Method
ETCO2	peroperative 2 hours	End-tidal carbon dioxide (ETCO2) level
po2	peroperative 2 hours	Arterial blood gas oxygen pressure

Trial Locations

Locations (1)

Bursa Yuksek Ihtisas Training and Research Hospital; 🇹🇷 Bursa, Turkey