Intratympanic Corticosteroid Therapy for Idiopathic Sudden Sensorineural Hearing Loss

Phase 4

Recruiting

• Conditions: Idiopathic Sudden Sensorineural Hearing Loss; Ear - Deafness

• Registration Number: ACTRN12622001555741
• Lead Sponsor: niversity of Melbourne

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2022-12-16
• Last Update Posted: 12 December 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

1. Idiopathic sudden sensorineural hearing loss (ISSNHL) defined as a history of a sudden decrease in hearing; not exceeding seven days in duration.
2. A sensorineural hearing loss demonstrable on a pure-tone audiogram at the time of entry into the trial (a 20 dB or more hearing loss in at least three frequencies compared to the healthy ear).
3. No otological pathological history or examination findings.
4. Absence of other neurological signs except the eighth cranial nerve defect.

Exclusion Criteria

1. All other types of sensorineural hearing loss, or conductive forms of hearing impairment.
2. A history of fluctuating sensorineural hearing loss.
3. Medical conditions rendering prescription of steroids unsafe. For example, patients with hypertension, diabetes, active peptic disease, pregnancy, chronic infections, uncompensated heart disease, recent surgery or psychiatric disease.

Study & Design

• Study Type: Interventional
• Study Design: Not specified