Combined Inspiratory Muscle and 'Whole Muscle' Training in Children With Cystic Fibrosis
- Conditions
- Cystic Fibrosis
- Interventions
- Other: Other
- Registration Number
- NCT01706445
- Lead Sponsor
- Universidad Europea de Madrid
- Brief Summary
To study the effects of an 8-week combined inspiratory muscle training and exercise (resistance+aerobic) program on of a lung volume, inspiratory muscle strength (maximal inspiratory pressure, PImax) and cardiorespiratory fitness (maximal oxygen uptake, VO2peak) (primary outcomes)and dynamic muscle strength, body composition and quality of life (QoL) in children with Cystic Fibrosis (CF) (secondary outcomes).
- Detailed Description
The investigators hypothesized that the combined training program would significantly benefit most of the aforementioned variables (especially, primary outcomes).
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 20
- boy/girl aged 6-17 years
- living in the Madrid area
- severe lung deterioration [forced expiratory volume (FEV1) <50% of expected]
- unstable clinical condition (hospitalization within the previous 3 months)
- Burkholderia cepacia infection
- any disorder (e.g. muscle-skeletal) impairing exercise.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description intervention Other Exercise training
- Primary Outcome Measures
Name Time Method cardiorespiratory fitness (VO2peak) this outcome will be assessed up to 12 weeks maximum oxygen uptake (VO2peak), which is the best indicator of aerobic fitness in humans and an independent mortality predictor in children with cystic fibrosis
- Secondary Outcome Measures
Name Time Method quality of life this outcome will be assessed up to 12 weeks children's QoL with the Spanish Version (1.0) of the Cystic Fibrosis Questionnaire-Revised (CFQ-R).
Trial Locations
- Locations (1)
Hospital Infantil Universitario Niño Jesús
🇪🇸Madrid, Spain