Comparative Study on the Effectiveness of Gandhak Druti and Gandhak Druti Ointment in Healing Infected Wounds (Dushta Vrana)

Phase 2

Not yet recruiting

• Conditions: Disorder of the skin and subcutaneous tissue, unspecified. Ayurveda Condition: DUSHTAVRANAH,

• Registration Number: CTRI/2025/04/086079
• Lead Sponsor: Dr.Aditi atul shah

Brief Summary

The management of *Dushta Vrana* (infected wounds) is a significant challenge in surgery, requiring wound cleansing, removal of necrotic tissue, and microbial control to ensure proper healing. While modern medicine offers many wound care options, Ayurvedic interventions are less explored. Ayurveda emphasizes *Vrana Shodhana* (wound cleansing) as detailed in texts like *Sushruta Samhita*, and Gandhak Druti—a herbo-mineral preparation—is noted for its wound healing potential. Previous studies suggest Gandhak Druti’s promising role, but direct clinical comparisons are limited. This study aims to evaluate and compare the effectiveness of Gandhak Druti and Gandhak Druti ointment in managing Dushta Vrana. Sixty patients will be divided into two groups and treated for one month, with weekly assessments based on subjective (pain, itching, burning) and objective (odor, color, exudate, wound size, granulation, slough) parameters. Drug preparation methods, diagnostic criteria, inclusion/exclusion guidelines, and thorough clinical monitoring have been outlined. The study aims to determine which form—liquid or ointment—is more effective in promoting healing and improving patient outcomes while contributing to affordable and accessible wound care solutions.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2025-04-30
• Study Start: 2025-06-23

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Patients of Dushta Vrana Patients who fulfilling diagnostic criteria Depth- Superficial to Full thickness wound Area of wound.
• maximum length more tha 10cm and width 10cm shape- all shapes.

Exclusion Criteria

If Patient is having Allergy to sulphur Patients with systemic infections Patients with Gangrene Burns wounds and wounds with malignance Patients with Uncontrolled Diabetes and tubercular ulcer.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Reduction in Pain, Itching, and Burning Sensation and wound healing upto granulation of tissue will be assessed according to scale	assessment should be done every weekly i.e 7th Day, 14th Day, 21th Day and 28th Day

Secondary Outcome Measures

Name	Time	Method
Improvement in skin color, odour, exudation level, size of wound, granulation and slough of wound	assessment should be done every weekly i.e 7th Day, 14th Day, 21th Day and 28th Day

Trial Locations

Locations (1)

Khemdas Hospital; 🇮🇳 Vadodara, GUJARAT, India

Khemdas Hospital

🇮🇳Vadodara, GUJARAT, India

Dr Aditi Atul Shah

Principal investigator

09404368606

aditishah9404@gmail.com