Recruitment of patient and constructing infrastructure of clinical research for depression in CNUH

Not Applicable

Completed

Conditions: Mental and behavioral disorders

Registration Number: KCT0001332

Lead Sponsor: Chonnam National University Hospital

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: All

Target Recruitment: 1262

Inclusion Criteria

1)Aged 7 or older
2)Hamilton Depression Rating Scale-17 (HAMD-17)>=14
3)Can understand the objective of the study and sign informed consent
4)If the subject is woman of childbearing age, the patient who does not plan to become pregnant and who uses appropriate contraceptive method
5)With ability to perform the procedure of study, administration of drug, visit to thi clinic as study protocol or with caretaker or clear officer who can help to perform the study procedure((eg, family, social workers, social work, volunteer, or nurse)

Exclusion Criteria

1)history of significantly unstable or uncontrollable medical condition, 2)unavailability to perform the psychiatric examination due to an acute physical illness
3)currently diagnosed or had history of other psychiatric disorder on Diagnostic and Statistical Manual of Mental Disorders, 4th edition (DSM-IV) Axis I : bipolar disorder, schizophrenia, schizoaffective disorder, schizophreniform disorder, psychotic disorder Not otherwise specified)

4)history of organic mental disorder, epilepsy or other convulsive disorder
5)history of prescribing anticonvulsant
6)patients needed hospitalization due to the psychiatric condition other than depression( abuse/dependence of alcohol/other substance)
7)history of Electroconvulsive therapy (ECT) for current depressive episode
8)Pregnancy or breastfeeding

Study & Design

Study Type: Interventional Study

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Hamilton depression rating scale

Secondary Outcome Measures

Name	Time	Method
Hospital Anxiety and Depression Scales;Clinical Global Impression;Social and Occupational Functioning Assessment Scale;Sheehan Disability Scale;suicide-related items on the Brief Psychiatric Rating Scale and the Schedule for Affective Disorders and Schizophrenia;EuroQol-5 Dimension;10-item short version of the Big Five Inventory;Multidimensional Scale of Perceived Social Support;modified Korean version of the Life Experiences Survey;Perceived Stress Scale;the Conner–Davidson Resilience Scale;Electrocardiogram/Resting blood pressure;Discrimination and Stigma Scale