Study for Multi-modal BrainNetwork Mechanisms and Long-term Effects of Acupuncture for Post-stroke Aphasia Based on the Theory of 'Integration of Body and Spirit'
- Conditions
- AphasiaR47.002
- Registration Number
- ITMCTR2000003121
- Lead Sponsor
- Dongzhimen Hospital affiliated to Beijing University of Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
1. Diagnosed as stroke through CT or MRI, 1 to 6 months after stroke onset;
2. Aged from 35 to 70 years, Native language is Chinese, righthanded;
3. Primary school and above education,No serious heart, liver or kidney diseases;
4. Clear consciousness, No cognition impairment;
5. The language function was normal before the onset, and the language dysfunction was dominant while the limb dysfunction was mild;
6. Specific Aphasia syndrome, diagnosed as motor aphasia by China Rehabilitation Research Center Aphasia Examination(CRRCAE);
7. The score of Boston Diagnostic Aphasia Examination(BDAE)is 2 to 4;
8. Being able to cooperate 30 minutes MRI examination.
1. Patients who have received pacemaker surgery, coronary intervention, coronary artery bypass surgery and other metal products in the body;
2. Patients who have serious heart, liver and kidney diseases or in a coma;
3. Language dysfunction caused by congenital or childhood diseases;
4. Language dysfunction caused by mental disturbance and normal mental retardation;
5. Severe dysarthria and hearing impairment;
6. Superficial sensation abnormalities in neurological examination;
7. Patients who have participated in other studies.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Magnetic Resonance Imaging;Severity of Aphasia;Language Function;Language Function;Electroencephalo-graph;
- Secondary Outcome Measures
Name Time Method Cognitive Abilit;Severity of Depression;Functional Neurological Impairments;Evaluation of clinical outcomes on stroke patients;Quality of Life;Disease prognosis of ischemic stroke;Activity of Daily Living;