A comparative clinical trial to assess combined effect of drakshadi ghrita aschyotana and shatavari ksheera paka paana internally versus shatavari ksheera paka internally in post menopausal women with dry eye disease.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Stability of the pre corneal tear film improves, Lubricates the occular surface hence reducing the symptoms of dry eye disease
研究概览
简要总结
Menopause is common natural transition phase in women’s life in which
the body greatly reduces oestogen synthesis which causes dry eyes along with
other psychosomatic disturbances. This accounts up to 52% of menopausal
women.
The DRY EYE DISEASE is multi factorial ocular surface disorder
usually caused by chronic inflammation and characterized by tear film instability
and increased osmolarity.
According to Ayurveda, DRY EYE DISEASE can be correlated with
Shushkakshipaka, a Vata-Pittaja pradhana Sarvagata netra roga.
Drakshadi ghrita aschyotana and Shatavari ksheerapaka paana will be
administered to the selected participants. The observations before and after the
treatment will be compared and assessed using OSDI scoring for Dry eye
diseaseand Schirmer’s test, TBUT and Serum Oestrogen level. Then results will
be statistically analyzed
So effect of these medicines is expected to give encouraging results by
jeevaneeya and chakshusya effects. Having phyto oestrogen, also helps in
regulation of oestrogen in general thus helping the reversal of Dry eye disease in
post menopausal women. The study can show new vista in the management of
post menopausal Dry eye disease by offering safe, effective affordable treatment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 45.00 Year(s) 至 55.00 Year(s)（—）
- 性别
- Female
入选标准
- •Women with complaints of Dry eye disease aged in between 45 -55 years with menstrual cessation for at least one year.
- •Menopausal Women with Dry eye disease complaints who are willing to participate in the study.
排除标准
- •Women below 45 years.
- •Recurrent eye inflammation.
- •History of trauma.
- •History of eye surgery within three months e.
- •Systemic illness including DM, HTN, PCOS f.
- •Malignancy, Psychiatric diseases other uro-genital diseases.
- •Women underwent surgical management for complete hysterectomy.
结局指标
主要结局
Stability of the pre corneal tear film improves, Lubricates the occular surface hence reducing the symptoms of dry eye disease
时间窗: 0th day, 60th day
次要结局
- Reducing the symptoms of dry eye disease - Grittiness, Blurred vision, Eye strain & increased light tolerance(60 days)
研究者
Dr Anita B Kulkarni
BVVS AYurved Medical College and Hospital Bagalkot