Laser Acupuncture in Egyptian Systemic Lupus Females With Insulin Resistance

Not Applicable

Recruiting

• Conditions: Systemic Lupus Erythematosus; PreDiabetes

• Registration Number: NCT05632029
• Lead Sponsor: Cairo University

Brief Summary

glucose hemosatasis, oxidative stress, abnormalities of blood pressures, and high inflammatory status is high presented in lupus patients.

Detailed Description

64 lupus prediabetic women will equally distributed to group A (n =32 that will receive laser acupuncture (active) for one month (3 days week) on acupoint number 14 of GV meridian, acupoint number 4 and 11 of large intestine, acupoint number 34 of gall bladder meridian, acupoint number 3 of liver meridian, acupoint number 4, 12, and 9 of conception vessel meridian, acupoint number 40, 36, and 25 of stomach meridian, acupoint number 6 of spleen meridian, and acupoint number 5 of triple energizer meridian, laser will be applied for 1 min on every acupiont) or group B (n =32 this group will receive the same protocol of group A but the points will be sham points)

Study Timeline

• Study Start: 2022-10-20
• Status Verified: 2022-11
• Study First Submitted: 2022-11-20
• Study First Submitted QC: 2022-11-20
• Last Update Submitted: 2022-11-20
• Study First Posted: 2022-11-30
• Last Update Posted: 2022-11-30
• Primary Completion: 2023-03-30
• Study Completion: 2023-03-30

Recruitment & Eligibility

• Status: RECRUITING
• Sex: Female
• Target Recruitment: 64

Inclusion Criteria

• prediabetic lupus females (n =64)

Exclusion Criteria

• obesity diabetes heart or respiratory problems

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Malondialdehyde	It will be measured after 4 weeks of laser application	oxidative stress indicator

Secondary Outcome Measures

Name	Time	Method
erythrocyte sedimentation rate (at first hour)	It will be measured after 4 weeks of laser application	it will be measured in serum
erythrocyte sedimentation rate (at second hour)	It will be measured after 4 weeks of laser application	it will be measured in serum
adenosine triphosphate	It will be measured after 4 weeks of laser application	it a measure for energy production
Nitrate	It will be measured after 4 weeks of laser application	it will be measured in serum
diastolic blood pressure	It will be measured after 4 weeks of laser application	manual sphygmomanometer
blood glucose	It will be measured after 4 weeks of laser application	it will be measured in fasting status
Glutathione	It will be measured after 4 weeks of laser application	it will be measured in serum
C reactive protein	It will be measured after 4 weeks of laser application	it will be measured in serum
systolic blood pressure	It will be measured after 4 weeks of laser application	manual sphygmomanometer

Trial Locations

Locations (1)

Cairo Unoversity; 🇪🇬 Giza, Egypt