Bumetanide Effect on SCI pain relief
Phase 1
- Conditions
- europathic pain in spinal cord injury.Injury of spinal cord, level unspecified
- Registration Number
- IRCT201407155368N2
- Lead Sponsor
- Brain and Spinal Cord Injury Research Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 15
Inclusion Criteria
Inclusion Criteria: All the patients with spinal cord injury and refractory at- or below-level pain due to the injury who signed the informed consent.
Exclusion Criteria
History of renal failure; Creatinine more than 1.5 mg/dl or its increase at least 0.5 mg/dl during study; Cardiovascular diseases including heart failure, conductive disorders and MI; Hypokalemia during study; During Breast feeding; History of hypersensitivity to sulfonamides, sulfunilurea, carbonic anhydrase inhibitors and thiazides; Using cross-reacting medications like Heart Glycosides, Cisplatin, Glucocorticoids, Cyclosporine, ACE Inhibitors, Aminoglycosides, Beta2 Agonists, Allopurinol, Dofetilide, Probenecid, Risperidone, Sodium Phosphates and Topiramate.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pain intensity. Timepoint: Time0, Month4, Month8. Method of measurement: Questionnaire.
- Secondary Outcome Measures
Name Time Method