Iatrogenic perforations during colonoscopy – mechanisms, therapy and clinical outcome – a retrospective, multicenter trial
- Conditions
- T81.2Accidental puncture and laceration during a procedure, not elsewhere classified
- Registration Number
- DRKS00028012
- Lead Sponsor
- Viszeralmedizinisches Zentrum, Evangelisches Diakoniekrankenhaus Freiburg
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 213
Inclusion Criteria
All perforations that occurred iatrogenically during colonoscopy, sigmoidoscopy or rectoscopy.
Exclusion Criteria
Perforation of the colon due to other causes (traumatic, inflammation, malignant, iatrogenic due to other medical measures)
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Endoscopic primär therapy (yes/no) and endoscopic primary therapy definitely successful (yes/no)
- Secondary Outcome Measures
Name Time Method mechanism of damage (diagnostic: tip of the endoscope, shaft of the endoscope, retroflection maneuver, biopsy / therapeutic: polypectomy, EMR, ESD, dilation/bouginage, electro-/thermocoagulation, others), type of damage (target sign, Sydney classification III/IV/V, covered, free), size (in cm), localisation (cecum, ascending/transverse/descending/sigmoid colon, rectum), time of diagnosis/therapy (intraprocedural/ delayed/late), clinical presentation, kind of primary therapy (conservative: monitoring, antibiotics/ drainage/ endoscopic: TTSC, OTSC, TTSC+loop, TTSC+OTSC, endosponge, SEMS/ surgery (laparotomy, laparoscopy): suturing, partial colonic resection, colectomy, stoma, drainage), primary therapy initially and definitely successful (yes/no), clinical appearance (no symptoms, pain, fever, inflammation markers day 1-5 (CRP, Leucocytes, Il-6)), kind of secondary therapy, secondary therapy successful (yes/no), death (yes/no), cause of death, duration of hospital stay (in days).