Acute Cerebrovascular Events in Patients Undergoing Catheter Ablation

Not yet recruiting

• Conditions: Arrhythmia; Acute Cerebrovascular Disease

• Registration Number: NCT05694273
• Lead Sponsor: First Affiliated Hospital Xi'an Jiaotong University

Brief Summary

This study aims to evaluate the incidence, clinical characteristics, and short-term prognosis of acute cerebrovascular events occurring in-hospital in patients with arrhythmias following catheter ablation. The goal is to provide evidence supporting the improvement of patient quality of life and reduction of in-hospital acute cerebrovascular complications in patients with post-ablation arrhythmias. This will also contribute to the evidence-based clinical management of such patients.

Detailed Description

With the steady development of catheter ablation, it has gradually become the main treatment of various arrhythmias. Antithrombotic and anticoagulant therapy after catheter ablation determines the occurrence of perioperative bleeding and ischemic events. However, the incidence, characteristics and short-term prognosis of secondary acute cerebrovascular events in patients with arrhythmia after catheter ablation have not been studied. Methods: This study was intended to retrospectively collect and analyze the case data and auxiliary examination results of patients with arrhythmia who underwent catheter ablation. To evaluate the incidence, clinical features and short-term prognosis of secondary acute ischemic and hemorrhagic cerebrovascular events in patients with arrhythmia after catheter ablation. In order to improve the quality of life of patients, reduce the secondary acute cerebrovascular complications in the hospital in patients with arrhythmia after catheter ablation, to provide evidence for promoting the clinical management of such patients, and to provide help for the maximum degree of prevention and control risk.

Study Timeline

• Study First Submitted: 2023-01-10
• Study First Submitted QC: 2023-01-12
• Study First Posted: 2023-01-23
• Status Verified: 2024-03
• Last Update Submitted: 2024-04-02
• Last Update Posted: 2024-04-04
• Study Start: 2025-01-15
• Primary Completion: 2026-12-01
• Study Completion: 2026-12-31

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 2000

Inclusion Criteria

• 1.Patients who undergo catheter ablation for arrhythmias.

Exclusion Criteria

• 1. Patients were diagnosed of acute cerebrovascular disease prior to radiofrequency catheter ablation;
• 2. Patients < 18 years or > 80 years;
• 3. Patients with uncomplete clinical data.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Incidence of MACCE	3 months after enrollment	Major adverse cardiovascular and cerebrovascular events, a composite of all-cause mortality, myocardial infarction and stroke. The data will be obtained at 3-month follow-up, according to medical records of all patients.

Secondary Outcome Measures

Name	Time	Method
Incidence of stroke	3 months after enrollment	The data will be obtained at 3-month follow-up, according to medical records of all patients.
Incidence of all-cause mortality	3 months after enrollment	The data will be obtained at 3-month follow-up, according to medical records of all patients.
Incidence of myocardial infarction	3 months after enrollment	The data will be obtained at 3-month follow-up, according to medical records of all patients.

Trial Locations

Locations (1)

First Affiliated Hospital of Xian Jiantong University; 🇨🇳 Xi'an, Shaanxi, China