Tranexamic acid versus etamsylate in reducing blood loss in patients with high risk of postpartum hemorrhage
Phase 1
- Conditions
- post partum hemorrhage
- Registration Number
- PACTR202205750416982
- Lead Sponsor
- October 6th university and Ain shams Maternity hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 180
Inclusion Criteria
All pregnant women who will give birth vaginally, full term of gestation age, susceptible for post-partum hemorrhage as: • History of pervious postpartum hemorrhage
precipitate labour or instrumental delivery or
prolonged induction of labour.
•Anemic (hemoglobin between 8-10mg/dl),
diabetic, macrosomic baby
Exclusion Criteria
Women with thrombophilia, or coagulopathy cardiovascular, renal, or liver disorders; or contraindication to any drug used in the study protocol as (allergy to TXA or its excipients)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1) The amount of blood loss measured by using the difference between pre weighted towels and weightof towels soaked with blood ,towels were weighed 2h postpartum Two digital scales of the same brandwill be calibrated by the biomedical engineeringdepartment, one placed in October 6th university hospital and the other one placed in Ain shams Maternity hospital. 2) Complete blood picture (CBC)<br>comparing hematocrit pre and postoperative and clinical data include blood pressure, pulse, andtemperature.
- Secondary Outcome Measures
Name Time Method The percentage of cases that developed postpartumhemorrhage, the need for blood transfusion and theneed for further interventions to combat postpartum<br>hemorrhage