TCTR20200715008尚未招募未知
Continuous Infusion vs. Intermittent Bolus Hydrocortisone Administration in Children with Catecholamine-Dependent Septic Shock: A Randomized Controlled Trial
none0 个研究点目标入组 108 人开始时间: 2020年7月15日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 尚未招募
- 发起方
- 入组人数
- 108
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 1 Months 至 18 Years（—）
- 性别
- All
入选标准
- •Children 1 month to 18 year of age admitted to PICU with catecholamine-dependent septic shock who are at risk for adrenal insufficiency as followings and received loading dose of hydrocortisone;
- •Risk for adrenal insufficiency:
- •- Physical signs e.g. purpura fulminans or diagnosed of Waterhouse-Friderichsen syndrome
- •- History of hypothalamic-pituitary-adrenal axis abnormalities e.g. congenital adrenal hyperplasia, pituitary gland disease
- •- History of corticosteroid use either long term (longer than 2 weeks within last 6 months) or short term (not longer than 2 weeks within last 4 month
- •- History of etomidate use
- •- History of antifungals use within last 7 days
排除标准
- •Hypersensitivity of hydrocortisone
- •Do-not-resuscitate patients
- •Post cardiac arrest
- •Patient receiving treatment with antifungals for systemic fungal infections at time of randomization
研究者
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