Dynamic Time Series Data Collection for Functional Recovery Changes in Sub-acute Stroke Patients
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Sub-acute Stroke
- Sponsor
- Samsung Medical Center
- Enrollment
- 94
- Locations
- 1
- Primary Endpoint
- Mechanism of recovery of motor function according to recovery of sub-acute stroke
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
In subacute stroke patients, dynamic time series data of brain imaging and motor function measurement were obtained from 7 days to 6 months (total 9 times) after stroke onset
Investigators
Eligibility Criteria
Inclusion Criteria
- •at least 19 years of age hemiplegic stroke patients
- •Subacute-phase ischemic or hemorrhagic stroke patients within 7 days of onset
- •Functional Ambulation Category Scale (FAC) of 3 or less, 7 days of onset,
- •A person who understands and voluntarily participates in this study and signs a research agreement
Exclusion Criteria
- •User of artificial heartbeat
- •Patients with claustrophobia
- •Patients with metal implants
- •Patients who are contraindicated for other common MRI
- •Patients with mild motor impairment with an FMA score of 80 or higher
- •Patients whose conscious state is coma and who have no response at all
- •Patients who can not independently gait with the Modified Rankin Scale (mRS) score of 4 or more before the onset of disease
Outcomes
Primary Outcomes
Mechanism of recovery of motor function according to recovery of sub-acute stroke
Time Frame: Through study completion, an average of 6 months
Mechanism of recovery of motor function calculate by repeated measurement method in physical and cognitive functions data and MRI data of brain
Mechanism of recovery of gait function according to recovery of sub-acute stroke
Time Frame: Through study completion, an average of 6 months
Mechanism of recovery of motor function calculate by repeated measurement method in 3D motion capture system and electromyography (EMG) data and MRI data of brain