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Botulinum toxin in the treatment of orofacial tardive dyskinesias: a single blind study

Completed
Conditions
Tardive dyskinesia
Nervous System Diseases
Dystonia
Registration Number
ISRCTN81508784
Lead Sponsor
Parnassia Psycho-medical Centre (Netherlands)
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
14
Inclusion Criteria

1. Patients suffering from orofacial tardive dyskinesias for at least 3 months
2. Stable dosage of psychopharmacological medication
3. Written informed consent by the patient

Exclusion Criteria

1. Age younger than 18 years
2. Contraindication for botulinum toxin (myasthenia gravis, Lambert Eaton Myasthenic Syndrome)
3. Women known to be pregnant or having a positive pregnancy test

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
1. Abnormal Involuntary Movement Scale (AIMS)<br>2. The number of patients that wanted to continue the treatment with botulinum toxin after cessation of the study
Secondary Outcome Measures
NameTimeMethod
1. Visual Analogue Scale <br>2. World Health Organization Quality Of Life, abbreviated version
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