Effects of Resistance-band Training and Creatine Supplementation in Healthy Older Adults
Trial Snapshot
- Phase
- Not Applicable
- Status
- Recruiting
- Sponsor
- University of Regina
- Enrollment
- 52
- Locations
- 1
- Primary Endpoint
- Power (feet)
Study Overview
Brief Summary
The primary purpose is to compare the effects of creatine supplementation (bolus ingestion of 5 grams vs. 3 grams) during 16 weeks of resistance-band training on measures of body composition (i.e., whole-body lean tissue mass, total body water), arm and leg muscle thickness (growth), muscle performance (i.e., power, strength, endurance) and functional ability (i.e., walking speed, balance).
A secondary purpose of this research is to examine the effects of bolus ingestion of creatine (5 grams) compared to intermittent ingestion of creatine (2 x 2.5 grams) during 16 weeks of resistance-band training on measures of body composition (i.e., whole-body lean tissue mass, total body water), arm and leg muscle thickness (growth), muscle performance (i.e., power, strength, endurance) and functional ability (i.e., walking speed, balance).
Detailed Description
Resistance-band training is safe, conveient, easy-to-use, eliminates potential barriers to exercise participation (i.e., lack of transportation to and from commercial training facilities) and results in high exercise compliance and adherence. Further, resistance-band training results in similar improvements in muscle performance and functional ability compared to traditional resistance-type training using free-weights and machines.
Creatine is a naturally occurring nitrogen-containing compound produced in the body in the liver and brain and can also be found in food products such as red meat and seafood or through commercially available manufactured creatine products.
Evidence-based research shows that creatine supplementation, when ingested during a resistance exercise training program, improves measures of lean mass and muscle growth, muscle performance and functional ability. However, the optimal creatine supplementation protocol to achieve these benefits is unknown.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Triple (Participant, Investigator, Outcomes Assessor)
Eligibility Criteria
- Ages
- 50 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •if you are 50 years of age and older
- •if you have not been performing more than 1 resistance training session per week for the past 6 weeks or more.
Exclusion Criteria
- •if you have taken creatine supplements within 30 days prior to the start of the study
- •if you have pre-existing allergies to the placebo (corn-starch maltodextrin).
Arms & Interventions
Creatine Bolus 5
Intervention: Creatine Bolus 5 (Dietary Supplement)
Creatine Bolus 3
Intervention: Creatine Bolus 3 (Dietary Supplement)
Creatine Intermittent 5
Intervention: Creatine Intermittent 5 (Dietary Supplement)
Placebo
Intervention: Placebo (Dietary Supplement)
Outcomes
Primary Outcomes
Power (feet)
Time Frame: baseline, week 16
medicine ball throw
Whole-body lean mass (kg)
Time Frame: baseline, week 16
Bioelectrical impedance analysis
Muscle Hypertrophy (cm)
Time Frame: baseline, week 16
B-mode ultrasound
Strength (kg)
Time Frame: baseline, week 16
1-repetition maximum leg press and chest press
Endurance (number of repetitions to fatigue)
Time Frame: baseline, week 16
Leg press and chest press
Balance (Centre of Pressure)
Time Frame: baseline, week 16
Force Plate
Gait Speed (meters)
Time Frame: baseline, week 16
Walking distance
Secondary Outcomes
No secondary outcomes reported
Investigators
Darren Candow
Professor
University of Regina