The effect of sedation with dexmedetomidine on the incidence of delirium after spinal anesthesia in elderly patients with hip surgery
- Conditions
- Diseases of the musculoskeletal system and connective tissue
- Registration Number
- KCT0003133
- Lead Sponsor
- Yonsei University, Wonju Severance Christian Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Withdrawn
- Sex
- All
- Target Recruitment
- 110
Patients scheduled to undergo a 65-year-old hip replacement with scheduled spinal anesthesia
- American Society of Anesthesiology grade 1,2,3 patients
- Under 65
- American society of Anesthesiology grade 4 or higher
- People who take Nore epinephrine reuptake inhibitors. (Eg tricyclic antidepressants, monoamine oxidation inhibitors, acute cocaine intoxication)
- myocardial infarction and stroke within the past one year
- Prior to major cardiac surgery within 1 year
- Patients who require vasodilators or oxygen therapy because they are anxious before surgery.
- Patients with fever (> 38 degrees)
- Patients with a history of drug hypersensitivity prior to sedation.
- Uncontrolled hypertension
- Patients who can not talk and have cognitive impairment
- Patients with a history of mental illness
- Brain damage, neurosurgical surgery.
- Preoperative Ejection fraction less than 30%, or a person with a heart rhythm disorder (Sick sinus syndrome, bradycardia less than 50 beats per minute, 2 or more degrees of atriovanetricular block without artificial heart rhythm.
- A patient with severe liver disease of Child-Pugh class C or higher.
- renal dysfunction with dialysis
- If the subject includes a person who can not read the consent form (eg, illiterate, foreigner, etc.)
- a patient have received other treatment or surgery.
- Those who have less chance of survival than 24 hours.
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method frequency of postoperative delirium
- Secondary Outcome Measures
Name Time Method the amount of bleeding