The effect of sedation with dexmedetomidine on the incidence of delirium after spinal anesthesia in elderly patients with hip surgery

Yonsei University, Wonju Severance Christian Hospital0 个研究点目标入组 110 人开始时间: 待定最近更新: 2021年7月12日

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•Patients scheduled to undergo a 65-year-old hip replacement with scheduled spinal anesthesia
•- American Society of Anesthesiology grade 1,2,3 patients

•- Under 65
•- American society of Anesthesiology grade 4 or higher
•- People who take Nore epinephrine reuptake inhibitors. (Eg tricyclic antidepressants, monoamine oxidation inhibitors, acute cocaine intoxication)
•- myocardial infarction and stroke within the past one year
•- Prior to major cardiac surgery within 1 year
•- Patients who require vasodilators or oxygen therapy because they are anxious before surgery.
•- Patients with fever (> 38 degrees)
•- Patients with a history of drug hypersensitivity prior to sedation.
•- Uncontrolled hypertension
•- Patients who can not talk and have cognitive impairment
•- Patients with a history of mental illness
•- Brain damage, neurosurgical surgery.
•- Preoperative Ejection fraction less than 30%, or a person with a heart rhythm disorder (Sick sinus syndrome, bradycardia less than 50 beats per minute, 2 or more degrees of atriovanetricular block without artificial heart rhythm.
•- A patient with severe liver disease of Child-Pugh class C or higher.
•- renal dysfunction with dialysis
•- If the subject includes a person who can not read the consent form (eg, illiterate, foreigner, etc.)
•- a patient have received other treatment or surgery.
•- Those who have less chance of survival than 24 hours.

发起方

Yonsei University, Wonju Severance Christian Hospital