Effect of keeping blood culture system inside neonatal ICU in decreasing antibiotics usage in newbor
Not Applicable
- Conditions
- Health Condition 1: P369- Bacterial sepsis of newborn, unspecified
- Registration Number
- CTRI/2021/12/038372
- Lead Sponsor
- All India institute of medical sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
All inborn neonates of the institute admitted in NICU warranting antibiotics for the first time
Exclusion Criteria
syndromic infants or infants with malformations, inability to collect blood culture before starting antibiotics, infants with suspected bone and joint infections, infants with surgical conditions warranting surgery
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method to compare the number of antibiotic dosage in neonates warranting antibiotics for suspected sepsis between two groupsTimepoint: discharge
- Secondary Outcome Measures
Name Time Method to compare number of antibiotics dosages in whole cohort including culture positive sepsis among the two groupsTimepoint: at discharge;to compare the blood culture positivity rate in both groupsTimepoint: at discharge;to compare the days of therapy in both groupsTimepoint: at discharge;to compare the duration of hospital stay in hours in both groupsTimepoint: at discharge;to compare the incidence of necrotising enterocolitis in both groupsTimepoint: at discharge;to compare the incidence of subsequent development of total sepsis, culture positive sepsis and fungal sepsisTimepoint: at discharge;to compare the mortality in both the groupsTimepoint: at discharge;To compare the number of neonates in which antibiotics were stopped at 48 hoursTimepoint: at discharge;to compare the time taken for detection of positive cultures in both groupsTimepoint: at discharge;to compare the time taken from blood collection to change of antibiotics as per sensitivity pattern in both groupsTimepoint: at discharge