The Effects of an Acute Sauna Session on Glucose Control in Individuals at Risk for Metabolic Impairments
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 15
- 试验地点
- 1
- 主要终点
- Incremental 2-hour postprandial glucose area under the curve (Breakfast)
研究概览
简要总结
The goal of this clinical trial is to examine the effect of a single 40-minute sauna session on glucose control in individuals at risk for metabolic impairments.
Research Questions:
- Can a single sauna session completed before a meal reduce the post-meal blood glucose response?
- Can a single sauna session improve 24-hour glucose control?
Study Design:
Participants will complete two lab visits: one involving a sauna session and one placebo visit (resting condition). Researchers will compare the effects on glucose control using a continuous glucose monitor (CGM).
What Participants Will Do:
Attend a sauna familiarization session Have a CGM sensor placed on the upper arm Visit the lab twice (once for sauna, once for placebo) Consume three standardized meals at home after each session
详细描述
At least 72 hours prior to the first trial, participants will complete a familiarization session consisting of two 20-minute infrared sauna exposures. The study employs a randomized crossover design, with each participant completing both experimental conditions-infrared sauna (two 20-minute sessions at 175°F / 79°C, separated by a 5-minute break) and seated rest (two 20-minute periods of quiet sitting, separated by a 5-minute break)-separated by at least 72 hours. On each trial day, participants will arrive at the laboratory at 7:50 a.m. after an overnight fast from 8:00 p.m., with water permitted throughout. Participants will wear a continuous glucose monitor (CGM) during both trial days. Baseline measurements of blood pressure, heart rate, and oral body temperature will be recorded, and food logs reviewed. Following the condition session, a sedentary recovery period will occur until 9:45 a.m., with repeated physiological measurements. Final measurements of blood pressure, heart rate, and oral body temperature will be collected prior to a standardized breakfast provided from 9:45 to 10:10 a.m. Participants will depart thereafter by car or public transportation and remain sedentary for the remainder of the day. Meals for the rest of the day, i.e., breakfast, lunch, dinner, and a bedtime snack, will be provided and identical across trial days. Participants will fast again from 9:00 p.m. until 9:00 a.m. the following morning.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 30 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Are 30-55 years old
- •Have a body mass index of ≥ 27 kg/m2
- •Have a waist size >102 cm (men) or >88 cm (women)
- •Have access to transportation for the 2 experimental visits (e.g., car, public transit, or drop-off).
- •Are cleared for participation based on the Physical Activity Readiness Questionnaire (PAR-Q+).
排除标准
- •Take medications that affect blood sugar
- •Exercise intensely 2+ times/week
- •Have diabetes, heart issues, low blood sugar or pressure
- •Are pregnant
- •Regularly use saunas or other heat therapy 1+ times/week
研究组 & 干预措施
Sauna
Infrared sauna session
干预措施: Infrared sauna session (Other)
Resting control
Seated resting session
干预措施: Resting condition (Other)
结局指标
主要结局
Incremental 2-hour postprandial glucose area under the curve (Breakfast)
时间窗: 2 hours
2-hour postprandial incremental AUC of CGM glucose above baseline, measured after the standardized breakfast consumed 45 minutes following the sauna or resting (control) session.
次要结局
- 2-hour postprandial glucose area under the curve (Breakfast)(2 hours)
- Incremental 2-hour postprandial glucose area under the curve (Lunch)(2 hours)
- Incremental 2-hour postprandial glucose area under the curve (Dinner)(2 hours)
- Incremental 2-hour postprandial glucose area under the curve (Bedtime snack)(2 hours)
- Average incremental 2-hour postprandial glucose area under the curve (4 meals)(2 hours)
- Time below range(24 hours)
- Time above range(24 hours)
- Time in range(24 hours)
- Session-induced delta glucose(45 minutes)
- Fasting glucose(15 minutes)
- Daily mean glucose(24 hours)