Local Infiltration Analgesia in Bilateral Knee Arthroplasty - Efficacy of Subcutaneous Wound Infiltration With Local Anesthetic

Phase 4

Completed

• Conditions: Pain, Postoperative
• Interventions: Drug: ropivacaine 0.2%, 50 mL; Drug: normal saline

• Registration Number: NCT00927225
• Lead Sponsor: Hvidovre University Hospital

Brief Summary

Local infiltration analgesia is effective in total knee arthroplasty for postoperative pain management, but the efficacy of subcutaneous wound infiltration has not been evaluated. This study aims at evaluating the efficacy of subcutaneous wound infiltration in total knee arthroplasty in 16 patients undergoing bilateral knee arthroplasty.

Detailed Description

Not available

Study Timeline

• Study Start: 2008-09
• Status Verified: 2009-06
• Primary Completion: 2009-06
• Study Completion: 2009-06
• Study First Submitted: 2009-06-23
• Study First Submitted QC: 2009-06-23
• Last Update Submitted: 2009-06-23
• Study First Posted: 2009-06-24
• Last Update Posted: 2009-06-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 16

Inclusion Criteria

• total bilateral knee arthroplasty

Exclusion Criteria

• immunological diseases
• treatment with opioids or steroids
• allergy to any drugs administered

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
active	ropivacaine 0.2%, 50 mL	subcutaneous wound infiltration with 50 mL ropivacaine 0.2%
placebo	normal saline	subcutaneous wound infiltration with 50 mL saline

Primary Outcome Measures

Name	Time	Method
Postoperative pain	1-6 hours postoperative

Trial Locations

Locations (1)

Hvidovre University Hospital; 🇩🇰 Hvidovre, Denmark