Clinical Trials/NCT00927225

NCT00927225

Completed

Phase 4

Local Infiltration Analgesia in Bilateral Knee Arthroplasty - Efficacy of Subcutaneous Wound Infiltration With Local Anesthetic.

Hvidovre University Hospital1 site in 1 country16 target enrollmentSeptember 2008

ConditionsPain, Postoperative

Interventionsropivacaine 0.2%, 50 mL normal saline

Drugsropivacaine 0.2%, 50 mL normal saline

Overview

Phase: Phase 4
Intervention: ropivacaine 0.2%, 50 mL
Conditions: Pain, Postoperative
Sponsor: Hvidovre University Hospital
Enrollment: 16
Locations: 1
Primary Endpoint: Postoperative pain
Status: Completed
Last Updated: 16 years ago

Overview Investigators Eligibility Criteria Arms & Interventions Outcomes Sites Similar Trials

Overview

Brief Summary

Local infiltration analgesia is effective in total knee arthroplasty for postoperative pain management, but the efficacy of subcutaneous wound infiltration has not been evaluated. This study aims at evaluating the efficacy of subcutaneous wound infiltration in total knee arthroplasty in 16 patients undergoing bilateral knee arthroplasty.

Registry

clinicaltrials.gov

Start Date

September 2008

End Date

June 2009

Last Updated

16 years ago

Study Type

Interventional

Study Design

Crossover

Sex

All

Investigators

Sponsor

Hvidovre University Hospital

Eligibility Criteria

Inclusion Criteria

•total bilateral knee arthroplasty

Exclusion Criteria

•immunological diseases
•treatment with opioids or steroids
•allergy to any drugs administered

Arms & Interventions

active

subcutaneous wound infiltration with 50 mL ropivacaine 0.2%

Intervention: ropivacaine 0.2%, 50 mL

placebo

subcutaneous wound infiltration with 50 mL saline

Intervention: normal saline

Outcomes

Primary Outcomes

Postoperative pain

Time Frame: 1-6 hours postoperative

Study Sites (1)

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