JPRN-UMIN000000920已完成未知
Feasibility study of adjuvant therapy with S-1 plus CDDP in gastric cancer - Feasibility study of adjuvant therapy with S-1 plus CDDP in gastric cancer
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 入组人数
- 63
研究概览
简要总结
A total of 63 enrolled patients have been evaluated. Grade 3/4 toxicities included neutropenia (40%), anorexia (28%), and febrile neutropenia (4%) before protocol amendment (n = 25), and neutropenia (37%), anorexia (8%), and febrile neutropenia (3%) after amendment implementation (n = 38). Excluding ineligible cases, treatment completion rates were 57% (12/21) before and 81% (30/37) after the protocol amendment.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 20years-old 至 75years-old（—）
- 性别
- All
入选标准
- 未提供
排除标准
- •1)synchronous or metachronous (within 5 years) malignancy other than carcinoma in situ 2)pregnant or breast-feeding women 3)severe mental disease 4)systemic administration of corticosteroids, flucytosine, phenytoin or warfarin 5)other severe complications, such as paralytic ileus, bowel obstruction, interstitial pneumonitis, pulmonary fibrosis, regular use of insulin or uncontrollable diabetes mellitus, arrhythmias, heart failure, liver cirrhosis, and active hepatitis) 6)myocardial infarction within the past 6 months 7)Inadequate physical condition, as diagnosed by primary physician
研究者
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