Evaluation of the Role of Poisoning Severity Score, Serum Procalcitonin and C-reactive Protein in Acute Hydrocarbon Intoxicated Cases Admitted to the Poison Control Center Ain Shams University Hospitals
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Serum procalcitonin level
研究概览
简要总结
Hydrocarbons are a primary energy source in modern society. They are present in many common household and occupational products, including motor fuels, paint thinners, cleaning agents, lotions, and industrial solvents. Unfortunately, these products are also used as agents of abuse and typically inhaled .
They are derived mainly from petroleum (kerosene, gas, naphtha) or wood (turpentine, pine oil). They can be found in liquid, gas, or solid form depending on their properties. All hydrocarbons can be toxic, but aromatic (ring-shaped) and halogenated hydrocarbons typically have more severe toxicity .
Toxicity occurs in various ways including through inhalation, ingestion, aspiration, and dermal exposure. Frequently, these exposures occur during attempted recreational use of the substances and sometimes for self-injurious behavior
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients of both sexes admitted to the Poison control center, Ain Shams university hospitals with acute hydrocarbon toxicity during the duration from December 2023 till December 2024 with a maximum number of 60 cases within 24 hours of intoxication.
排除标准
- •Patients with these criteria will be excluded:
- •Cases > 24 hours of intoxication.
- •Cases with occupational exposure to hydrocarbons.
- •Pregnant females.
- •Any cases received any treatment before arrival to the PCC.
- •Cases suffering from cardiac, respiratory, renal, hepatic or haematological disorders.
- •Cases presenting with fever.
- •Cases with other causes that can increase levels of CRP & pro-calcitonin as bacterial infection, recent major trauma, major burn ,septic shock and medullary thyroid cancer.
结局指标
主要结局
Serum procalcitonin level
时间窗: 1 year
measuring the level of serum procalcitonin (reference range 0-0.05µg/L)
次要结局
未报告次要终点
研究者
Mera Gergis khalil
assistant lecteurer Forensic medicine and Toxicology department sohag univerisity hospital
Sohag University
