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A clinical trial to assess whether the new nerve repair technique (PEG fusion) is safe and effective in adults with traumatic complete cuts involving large nerves in the forearm.

Phase 2
Recruiting
Conditions
Peripheral nerve injuries
Registration Number
SLCTR/2021/029
Lead Sponsor
Dr. Gayan Ekanayake
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Not specified
Target Recruitment
20
Inclusion Criteria

a.Age 18 years to 60 years
b. Both males and females
c.Admitted to accident and orthopedic services department of National Hospital of Sri Lanka
d.Sustaining single complete cut injury to median and/or ulnar nerve at forearm (defined as the nerve is cut at or in between distal wrist crease and elbow flexion crease due to a sharp cutting mechanism. e.g., glass, sword, sharp knife)
e.Nerve repair performed within 72 hours from the time of injury

Exclusion Criteria

a.Patients who are unable to provide valid informed consent
b.Patients sustaining injury to both radial and ulnar arteries in addition to nerve injury
c.Patients sustaining simultaneous bilateral upper limb nerve/ tendon injury
d.Patients with any past history of significant injury or disability of contralateral upper limb

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
• Parameter- Disability after nerve repair with PEG fusion<br>• Tool- DASH questionnaire <br>Reference- DASH | Welcome to our website where you will find up-to-date information about the DASH Outcome Measure, the QuickDASH and related DASH [Internet]. [cited 2021 Jun 7]. Available from: https://dash.iwh.on.ca<br><br> [Post-operative week 12, 24 36, and 48.]<br>• Parameter- Functional and aesthetic outcome following nerve repair with PEG fusion<br>• Tool- Michigan Hand Questionnaire<br>Reference- KC, Pillsbury MS, Walters MR, Hayward RA. Reliability and validity testing of the Michigan Hand Outcomes Questionnaire. J Hand Surg. 1998 Jul 1;23(4):575–87.<br> [Post-operative week 12, 24, 36 and 48.]<br>• Parameter- Adverse outcomes following nerve repair with PEG fusion using clinical assessment<br> [ Any timepoint up to 48 weeks post-operatively]<br> []<br> []<br>
Secondary Outcome Measures
NameTimeMethod
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