A multi-faceted intervention to enhance cognition in older people at risk of cognitive decline: the Protein, Omega-3 aNd vitamin D Exercise Research (PONDER) study

Deakin University0 个研究点目标入组 148 人开始时间: 2016年11月10日最近更新: 2020年8月17日

适应症

试验速览

暂无简介。

•1. Healthy adults aged 60 to 85
•2. Subjective memory complaints defined as a positive response to the question do you feel like your memory is becoming worse?” and a score of >17 on the Montreal Cognitive Assessment.
•3. Fluent in written and spoken English
•4. Normal, or corrected to normal vision and hearing

•1. Diagnosis of Alzheimer’s disease or other dementia, parkinson’s disease
•2 .Past history of brain damage including significant head trauma, stroke, or
•serious neurological disorder
•3. Clinical diagnosis of psychiatric disorder likely to affect cognition
•4. Alcohol or drug dependency within the last 2 years
•5. Existing diagnosed gastrointestinal disorders likely to impact absorption of fatty acids
•6. Known allergy to fish or any other component in the dietary supplement
•7. Insufficient mobility to exercise
•8. Body mass index >40
•9. Current smokers
•10. Participating in progressive resistance training >1 week or more >150 minutes per week of moderate intensity physical activity
•11. Daily use of omega-3 rich supplement, or vitamin D supplements >500 IU within the past 12 weeks
•12. Use of cholinesterase inhibitors, benzodiazepines, antipsychotics, high dose antidepressants, warfarin or high dose blood thinners
•13. Resistance hypertension
•14. Type 2 diabetes
•15. Oily fish consumption (>1/week)

发起方