The effects of combining omega-3, vitamin D and protein with exercise on cognition in older people

Not Applicable

Active, not recruiting

• Conditions: Dementia; Frailty; Neurological - Studies of the normal brain and nervous system; Mental Health - Studies of normal psychology, cognitive function and behaviour; Age-related cognitive decline; Musculoskeletal - Normal musculoskeletal and cartilage development and function

• Registration Number: ACTRN12616001549415
• Lead Sponsor: Deakin University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-11-10
• Last Update Posted: 17 August 2020

Recruitment & Eligibility

• Status: Active, not recruiting
• Sex: All
• Target Recruitment: 148

Inclusion Criteria

1. Healthy adults aged 60 to 85
2. Subjective memory complaints defined as a positive response to the question do you feel like your memory is becoming worse?” and a score of >17 on the Montreal Cognitive Assessment.
3. Fluent in written and spoken English
4. Normal, or corrected to normal vision and hearing

Exclusion Criteria

1. Diagnosis of Alzheimer’s disease or other dementia, parkinson’s disease
2 .Past history of brain damage including significant head trauma, stroke, or
serious neurological disorder
3. Clinical diagnosis of psychiatric disorder likely to affect cognition
4. Alcohol or drug dependency within the last 2 years
5. Existing diagnosed gastrointestinal disorders likely to impact absorption of fatty acids
6. Known allergy to fish or any other component in the dietary supplement
7. Insufficient mobility to exercise
8. Body mass index >40
9. Current smokers
10. Participating in progressive resistance training >1 week or more >150 minutes per week of moderate intensity physical activity
11. Daily use of omega-3 rich supplement, or vitamin D supplements >500 IU within the past 12 weeks
12. Use of cholinesterase inhibitors, benzodiazepines, antipsychotics, high dose antidepressants, warfarin or high dose blood thinners
13. Resistance hypertension
14. Type 2 diabetes
15. Oily fish consumption (>1/week)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Cognitive function assessed using the CogState battery and the Trail Making Test[baseline, 6 months]