Feasibility Study of Culturally Adapted Cognitive Behavior Therapy for Psychosis in Pakistan
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 36
- 试验地点
- 1
- 主要终点
- Positive and Negative syndrome scale (PANSS)
研究概览
简要总结
Aim:
To assess the feasibility of application of culturally-adapted CBT (CaCBTp) for use in Pakistan.
Design:
Randomized Control Trial
Setting:
Psychiatry Departments of General Hospitals in Karachi.
Participants:
A total of 36 patients with a diagnosis of psychotic disorder will be randomized to a psychological intervention or treatment as usual arm.
Intervention:
Culturally Adapted Cognitive Behavioral Therapy (CBT)
Outcome measure:
Positive and Negative syndrome scale (PANSS) Psychotic symptoms Rating Scales (PSYRATS)
详细描述
The purpose of the study is to test the feasibility of culturally adaptive CBT for Psychosis in Pakistan
Primary :
-To assess the feasibility of application of culturally-adapted CBT (CaCBTp) for use in Pakistan.
Secondary:
- To assess fidelity of culturally-adapted CBT for psychosis.
- To further modify CaCBTp in accordance with findings of feasibility study
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosis of Psychosis established by clinician using ICD10 criteria.
- •Individuals aged between 18-
- •Should not have learning disability.
- •Resident of Karachi.
- •Participant is able to give informed written consent
排除标准
- •Severe illness which may affect capacity or markedly affect their ability to participate in interview, e.g. very thought disordered or distressed by symptoms.
- •Severe drug or alcohol problem (i.e., those who fulfill the criteria for dependence according to ICD10 RDC).
研究组 & 干预措施
Intervention
Culturally Adapted Cognitive Behavior Therapy
干预措施: Culturally Adapted Cognitive behavior therapy (Behavioral)
Control
Patients who will be randomized to the "treatment as usual" arm will receive routine care
结局指标
主要结局
Positive and Negative syndrome scale (PANSS)
时间窗: up to 6 months
The PANSS is a structured clinical interview consisting of 30 items designed to assess severity of symptoms over the past week on a 7-point scale.
次要结局
- Calgary Depression Scale for Schizophrenia(Baseline ,3 months & 6 months)
- Psychotic Symptom Rating Scales (PSYRATS)(Baseline ,3 months & 6 months)
- Insight rating scale(Baseline ,3 months & 6 months)
- Short Explanatory Model Interview(Baseline ,3 months & 6 months)