CT Coronary Angiography and Computational Fluid Dynamics
- Conditions
- Coronary Artery Disease
- Interventions
- Device: CT coronary angiography and computational fluid dynamics
- Registration Number
- NCT01189331
- Lead Sponsor
- Seoul National University Hospital
- Brief Summary
Angiographically obtained fractional flow reserve(FFR) could provide functional and clinical information about stenotic lesion, but the invasiveness and measuring difficulty of FFR make it unfamiliar to perform. CT coronary angiography is non-invasive tool to evaluate lesion severity and lately developing computational fluid dynamics could provide functional information. The investigators build a patient specific model of computational fluid dynamics by CT coronary angiography and evaluate the functional significance by measuring fractional flow reserve via CT coronary angiography and computational fluid dynamics, and investigate its long-term prognostic implications.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 103
- Significant stenosis at CT angiography
- Normal ejection fraction on echocardiography
- Informed consented patient
- total occlusion and collateral flow to target vessel
- AV conduction abnormality
- Left ventricular hypertrophy
- significant valvular heart or primary myocardial disease
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description CT and FFR CT coronary angiography and computational fluid dynamics -
- Primary Outcome Measures
Name Time Method target vessel failure 10 year composite of cardiovascular death, target vessel myocardial infarction, target vessel revascularization
fractional flow reserve 1day fractional flow reserve of stenotic coronary artery
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Seoul National University Hospital
🇰🇷Seoul, Korea, Republic of