Short-term Effect of Kefir-fermented Milk Consumption on Bone Mineral Density and Bone Metabolism in Osteoporotic Patients

Ministry of Science and Technology, Taiwan0 sites69 target enrollmentMay 2010

ConditionsOsteoporosis

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Osteoporosis
Sponsor: Ministry of Science and Technology, Taiwan
Enrollment: 69
Primary Endpoint: bone mineral density and bone regeneration
Status: Completed
Last Updated: 10 years ago

Overview Investigators Eligibility Criteria Outcomes Similar Trials

Overview

Brief Summary

In a controlled, parallel, double-blind intervention study over 6 months, the investigators investigated the effects of kefir-fermented milk (1,600 mg/kg) supplemented with calcium bicarbonate (CaCO3, 1,500 mg/kg) and bone metabolism in 40 osteoporosis patients, and compared them with CaCO3 alone without kefir supplements. Bone turnover markers were measured in fasting blood samples collected before therapy and at 1, 3, and 6 months. BMD values at the spine, total hip, and hip femoral neck were assessed by dual-energy x-ray absorptiometry (DXA) at baseline and at 6 months.

Registry

clinicaltrials.gov

Start Date

May 2010

End Date

January 2012

Last Updated

10 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Ministry of Science and Technology, Taiwan

Responsible Party

Principal Investigator

Min-Yu Tu

Ministry of Science and Technology

Ministry of Science and Technology, Taiwan

Eligibility Criteria

Inclusion Criteria

•Clinical diagnosis of osteoporosis patients

Exclusion Criteria

•Any previous use of parathyroid hormone or sodium fluoride, use of anabolic steroids or growth hormone within 6 months before trial entry or oral or intravenous systemic corticosteroids within 12 months, and any previous use of strontium.